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NGC-1213 - Care of the patient with amblyopia.

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Guideline:Care of the patient with amblyopia. Measure Summary

National Guideline Clearinghouse (NGC). Guideline summary: Care of the patient with amblyopia. In: National Guideline Clearinghouse (NGC) [Web site]. Rockville (MD): cited 1994 (revised 1998; reviewed 2009). Available: http://www.guideline.gov.

NOTE: This guideline summary content is published by the National Guidelines Clearinghouse (NGC), in cooperation with the guideline authoring organization(s). For additional guideline resources, visit www.NGC.gov. Neither NGC or the original guideline authoring organization(s) approve of or endorse any product or service offered on this website. These NGC guideline summaries reside in the public domain and are displayed by GuidelineCentral.com as a convenient reference service for our customers visiting this website.

Guideline Title
Care of the patient with amblyopia.
Bibliographic Source(s)
American Optometric Association. Care of the patient with amblyopia. St. Louis (MO): American Optometric Association; 1998. 56 p. [177 references]
Guideline Status

This is the current release of the guideline.

According to the guideline developer, this guideline was last reviewed for currency in 2009.

Scope

Disease/Condition(s)

Amblyopia

Guideline Category
Diagnosis

Evaluation

Management
Clinical Specialty
Optometry
Intended Users
Health Plans

Optometrists
Guideline Objective(s)
  • To identify patients at risk of developing amblyopia
  • To accurately diagnose amblyopia
  • To improve the quality of care rendered to patients with amblyopia
  • To minimize the adverse effects of amblyopia
  • To preserve the gains obtained through treatment
  • To inform and educate parents, patients, and other health care practitioners about the visual complications of amblyopia and the availability of treatment
Target Population

Children and adults suspected of having amblyopia

Interventions and Practices Considered

Diagnosis of Amblyopia

  1. Patient History
  2. Ocular Examination
    • Visual Acuity
    • Refraction
    • Monocular fixation
    • Ocular motor deviation
    • Sensorimotor fusion
    • Accommodation
    • Ocular motility
    • Ocular health assessment and systemic health screening

Management of Amblyopia

  1. Optical Correction
  2. Occlusion
  3. Active Vision Therapy
  4. Patient Education
Major Outcomes Considered

Not stated

Methodology

Methods Used to Collect/Select the Evidence
Hand-searches of Published Literature (Primary Sources)

Searches of Electronic Databases
Description of Methods Used to Collect/Select the Evidence

The guideline developer performed literature searches using the National Library of Medicine's Medline database and the VisionNet database.

2009 Review Process

The principal author of the guideline and primary American Optometric Association staff performed searches of PubMed and Cochrane Collaboration using relevant keywords. The Clinical Guidelines Coordinating Committee reviews staff literature searches conducted for each guideline. The committee then determines which guidelines should be reviewed by the consensus panel, revised by the principal author and panel, or completely rewritten.

Number of Source Documents

Not stated

Methods Used to Assess the Quality and Strength of the Evidence
Expert Consensus (Committee)
Rating Scheme for the Strength of the Evidence

Not stated

Methods Used to Analyze the Evidence
Review
Description of the Methods Used to Analyze the Evidence

Not applicable

Methods Used to Formulate the Recommendations
Not stated
Rating Scheme for the Strength of the Recommendations

Not applicable

Cost Analysis

A formal cost analysis was not performed and published cost analyses were not reviewed.

Method of Guideline Validation
Internal Peer Review
Description of Method of Guideline Validation

The Reference Guide for Clinicians was reviewed by the American Optometric Association (AOA) Clinical Guidelines Coordinating Committee and approved by the AOA Board of Trustees.

Recommendations

Major Recommendations

Summarized by the National Guideline Clearinghouse (NGC):

Diagnosis of Amblyopia

The evaluation of a patient with amblyopia may include, but is not limited to the following areas. These examination components are not intended to be all inclusive because professional judgment and the individual patient's symptoms and findings may have a significant impact on the nature, extent, and course of the services provided. Each component is described in greater detail in the guideline document.

Potential Components of the Diagnostic Evaluation for Amblyopia

  1. Patient History
  2. Visual acuity
  3. Refraction (noncycloplegic and cycloplegic)
  4. Monocular fixation
  5. Ocular motor deviation
  6. Sensorimotor fusion
  7. Accomodation
  8. Ocular motility
  9. Ocular health assessment and systemic health screening
  10. Supplemental testing
    1. Electrodiagnostic testing
    2. Additional differential diagnostic testing

Management of amblyopia

Treatment should be directed toward the two primary etiologies of amblyopia: form deprivation and binocular inhibition. Amblyopia therapy effectively restores normal or near-normal visual function by eliminating eccentric fixation and/or developing more extensive synaptic input to the visual cortex. It improves monocular deficits of visual acuity, monocular fixation, accommodation, and ocular motility. The final step in amblyopia therapy, if possible, is to develop normal binocular vision. The establishment of binocular vision eliminates or significantly reduces the underlying binocular inhibition in unilateral amblyopia, which increases the probability of maintaining visual acuity improvements.

The following treatment options are discussed in greater detail in the guideline document:

  • Optical correction
  • Occlusion
  • Active vision therapy

Management of deprivation amblyopia, isometropic amblyopia, anisometropic amblyopia, and strabismic amblyopia are discussed in greater detail in the guideline document.

The frequency and composition of evaluation and management visits for amblyopia are summarized in the following table:


Type of Patients

Evaluation Visits

Prognosis1

Treatment Options2

Frequency of FU visits

Estimated Total VT visits3

Composition of FU Evaluations

VA REF MF BS

Monocular Form
Deprivation
Amblyopia
1-2 Fair, (if diagnosed and treated during critical period)
  1. Surgery, optical correction
  2. Surgery, optical correction, visual stimulation
  1. Every 2-4 wks for 1 yr; every 6 mos thereafter
  2. Every 2-4 wks for 1 yr; every 6 mos thereafter
Each visit Each visit -------- Each visit
Binocular Form Deprivation Amblyopia 1-2 Fair, (if diagnosed and treated during critical period)
  1. Surgery, optical correction
  2. Surgery, optical correction, visual stimulation
  1. Every 2-4 wks for 1 yr; every 6 mos thereafter
  2. Every 2-4 wks for 1 yr; every 6 mos thereafter
Each visit Each visit -------- Each visit
Isometropic Refractive Amblyopia 1-2 Good
  1. Optical correction
  2. Optical correction, vision therapy
  1. Reevaluate in 4-6 wks;
  2. Reevaluate in 4-6 wks; 2-6 mos FU after VT
10-15 Each visit PRN PRN Each visit
Anisometropic
Refractive Amblyopia
1-2 Good
  1. Optical correction
  2. Optical correction occlusion (part-time)
  3. Optical correction occlusion (part-time) vision therapy
  1. Reevaluate in 4-6 wks; every 2-6 mos FU
  2. Reevaluate in 4-6 wks; every 2-4 wks FU
  3. Reevaluate in 4-6 wks; 2-6 mos FU after VT
15-25 Each visit PRN PRN Each visit
Strabismic Amblyopia (Central Fixation) 1-2 Good
  1. Optical correction, occlusion
  2. Optical correction, occlusion, vision therapy
  1. Re-evaluate in 4-6 wks; every 2-4 wks FU
  2. Re-evaluate in 4-6 wks; 2-6 mos FU after VT
15-25 Each visit PRN PRN Each visit
Strabismic Amblyopia (Eccentric Fixation) 1-2 Fair
  1. Optical correction, occlusion
  2. Optical correction, occlusion, vision therapy
  1. Re-evaluate in 4-6 wks; every 2-4 wks FU
  2. Re-evaluate in 4-6 wks; 2-6 mos FU after VT
25-35 Each visit PRN Each visit Each visit

1

General prognosis; prognosis is improved during critical sensitive period of development, but compliance and motivation afford improvements into adulthood.
2Surgery is indicated in cases of congenital cataract and ptosis.
3Estimated visits may vary based on co-existing conditions, patient compliance, etc.

VA = visual acuity, REF = refractive status, MF = monocular fixation, BS = binocular status, FU = follow-up visit, VT = vision therapy, PRN = as necessary

Clinical Algorithm(s)

An algorithm is provided for Optometric Management of the Patient with Amblyopia.

Evidence Supporting the Recommendations

Type of Evidence Supporting the Recommendations

The type of supporting evidence is not specifically stated for each recommendation.

Benefits/Harms of Implementing the Guideline Recommendations

Potential Benefits

The prevalence, potential risks, and possible costs of untreated amblyopia contrasted with the good prognosis for patients treated at any age necessitate the involvement of optometrists in the diagnosis and treatment, or referral for consultation of patients with amblyopia.

Potential Harms

Not stated

Qualifying Statements

Qualifying Statements

Clinicians should not rely on this Clinical Guideline alone for patient care and management. Please refer to the references and other sources listed in the original guideline for a more detailed analysis and discussion of research and patient care information.

Implementation of the Guideline

Description of Implementation Strategy

An implementation strategy was not provided.

Institute of Medicine (IOM) National Healthcare Quality Report Categories

IOM Care Need
Getting Better

Staying Healthy
IOM Domain
Effectiveness

Patient-centeredness

Identifying Information and Availability

Bibliographic Source(s)
American Optometric Association. Care of the patient with amblyopia. St. Louis (MO): American Optometric Association; 1998. 56 p. [177 references]
Adaptation

Not applicable: The guideline was not adapted from another source.

Date Released
1994 (revised 1998; reviewed 2009)
Guideline Developer(s)
American Optometric Association - Professional Association
Source(s) of Funding

Funding was provided by the Vision Service Plan (Rancho Cordova, California) and its subsidiary Altair Eyewear (Rancho Cordova, California)

Guideline Committee

American Optometric Association Consensus Panel on Care of the Patient with Amblyopia

Composition of Group That Authored the Guideline

Members: Michael W. Rouse, O.D., M.S. (Principal Author); Jeffrey S. Cooper, O.D., M.S.; Susan A. Cotter, O.D.; Leonard J. Press, O.D.; Barry M. Tannen, O.D.

AOA Clinical Guidelines Coordinating Committee Members: John F. Amos, O.D., M.S. (Chair); Kerry L. Beebe, O.D.; Jerry Cavallerano, O.D., Ph.D.; John Lahr, O.D.; Richard Wallingford, Jr., O.D.

Financial Disclosures/Conflicts of Interest

Not stated

Guideline Status

This is the current release of the guideline.

According to the guideline developer, this guideline was last reviewed for currency in 2009.

Guideline Availability

Electronic copies: Available from the American Optometric Association Web site .

Print copies: Available from the American Optometric Association, 243 N. Lindbergh, Blvd., St. Louis, MO 63141-7811

Availability of Companion Documents

None available

Patient Resources

The following is available:

  • Answers to your questions about lazy eye. St. Louis, MO: American Optometric Association. (Patient information pamphet).

Print copies: Available from the American Optometric Association, 243 N. Lindbergh Blvd., St. Louis, MO 63141-7881; Web site, www.aoanet.org .

Please note: This patient information is intended to provide health professionals with information to share with their patients to help them better understand their health and their diagnosed disorders. By providing access to this patient information, it is not the intention of NGC to provide specific medical advice for particular patients. Rather we urge patients and their representatives to review this material and then to consult with a licensed health professional for evaluation of treatment options suitable for them as well as for diagnosis and answers to their personal medical questions. This patient information has been derived and prepared from a guideline for health care professionals included on NGC by the authors or publishers of that original guideline. The patient information is not reviewed by NGC to establish whether or not it accurately reflects the original guideline's content.

NGC Status

This summary was completed by ECRI on December 2, 1999. The information was verified by the guideline developer as of January 27, 2000. The information was reaffirmed by the guideline developer in 2009 and updated by ECRI Institute on February 26, 2010.

Copyright Statement

This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions as follows:

Copyright to the original guideline is owned by the American Optometric Association (AOA). NGC users are free to download a single copy for personal use. Reproduction without permission of the AOA is prohibited. Permissions requests should be directed to Jeffrey L. Weaver, O.D., Director, Clinical Care Group, American Optometric Association, 243 N. Lindbergh Blvd., St. Louis, MO 63141; (314) 991-4100, ext. 244; fax (314) 991-4101; e-mail, ClinicalGuidelines@theAOA.org.

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Guidelines represented on the NGC Web site are submitted by guideline developers, and are screened solely to determine that they meet the NGC Inclusion Criteria which may be found at http://www.guideline.gov/about/inclusion-criteria.aspx.

NGC, AHRQ, and its contractor ECRI Institute make no warranties concerning the content or clinical efficacy or effectiveness of the clinical practice guidelines and related materials represented on this site. Moreover, the views and opinions of developers or authors of guidelines represented on this site do not necessarily state or reflect those of NGC, AHRQ, or its contractor ECRI Institute, and inclusion or hosting of guidelines in NGC may not be used for advertising or commercial endorsement purposes.

Readers with questions regarding guideline content are directed to contact the guideline developer.

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