The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening examinations for dental caries performed by primary care clinicians in children from birth to age 5 years.
Frequency of Service
No information available.
Risk Factor Information
All children are at potential risk for dental caries; those whose primary water supply is deficient in fluoride (defined as containing <0.6 ppm F) are at particular risk. While there are no validated multivariate screening tools to determine which children are at higher risk for dental caries, there are a number of individual factors that elevate risk. Higher prevalence and severity of dental caries are found among minority and economically disadvantaged children. Other risk factors for caries in children include frequent sugar exposure, inappropriate bottle feeding, developmental defects of the tooth enamel, dry mouth, and a history of previous caries. Maternal and family factors can also increase children's risk. These factors include poor oral hygiene, low socioeconomic status, recent maternal caries, sibling caries, and frequent snacking. Additional factors associated with dental caries in young children include lack of access to dental care; inadequate preventive measures, such as failure to use fluoride-containing toothpastes; and lack of parental knowledge about oral health.
Patient Population Under ConsiderationThis recommendation applies to children age 5 years and younger.
The USPSTF limited its consideration of caries screening and prevention by primary care clinicians to infants and preschool-aged children. The rationale for this decision was that, at the present time, nondental primary care clinicians are more likely than dentists to have contact with children ages 5 years and younger in the United States; this situation changes as children reach school age and beyond. In addition, as children grow older, dental professionals use sealants rather than fluoride varnish. As such, the USPSTF limited its review of the evidence of preventive interventions for dental caries to this age group. This recommendation should not be construed to imply that preventive interventions for dental caries should cease after 5 years of age.
Assessment of RiskAll children are at potential risk for dental caries; those whose primary water supply is deficient in fluoride (defined as containing <0.6 ppm F) are at particular risk. While there are no validated multivariate screening tools to determine which children are at higher risk for dental caries, there are a number of individual factors that elevate risk. Higher prevalence and severity of dental caries are found among minority and economically disadvantaged children. Other risk factors for caries in children include frequent sugar exposure, inappropriate bottle feeding, developmental defects of the tooth enamel, dry mouth, and a history of previous caries. Maternal and family factors can also increase children's risk. These factors include poor oral hygiene, low socioeconomic status, recent maternal caries, sibling caries, and frequent snacking. Additional factors associated with dental caries in young children include lack of access to dental care; inadequate preventive measures, such as failure to use fluoride-containing toothpastes; and lack of parental knowledge about oral health.
Some organizations have advocated restricting fluoride varnish use to children at “increased risk.” Although several caries risk assessment tools exist, none have been validated in the primary care setting, nor do existing studies demonstrate that these tools, when used by primary care clinicians, can accurately and consistently differentiate between children who will develop dental caries and those who will not. A risk-based approach to fluoride varnish application will miss opportunities to provide an effective dental caries preventive intervention to children who could benefit from it, particularly because currently, in the United States, infants and preschool-aged children are more likely to have regular visits with nondental primary care clinicians than dental care providers.
Interventions to Prevent Dental CariesAs noted previously, oral fluoride supplementation prevents dental caries in patients with inadequate water fluoridation.
All children with erupted teeth can potentially benefit from the periodic application of fluoride varnish, regardless of the levels of fluoride in their water. Though the evidence to support varnish is drawn from higher-risk populations, the provision of varnish to all children is reasonable since the prevalence of risk factors is high in the U.S. population, the number needed to treat is low, and the harms of the intervention are small to none.
The USPSTF did not review the evidence on the effectiveness of tooth brushing, but regular tooth brushing with fluoride toothpaste by children is very important in preventing dental caries.
Timing and Dosage of Preventive InterventionsNo studies specifically addressed the dosage and timing of oral fluoride supplementation in children with inadequate water fluoridation. The American Dental Association (ADA) recommendations on the dosage of and age at which to start dietary fluoride supplementation take into account the amount of fluoride in the child's water source. These dosing recommendations are also referenced by the American Academy of Pediatrics (AAP).
No study directly assessed the appropriate ages at which to start and stop the application of fluoride varnish. Available trials of fluoride varnish enrolled children ages 3 to 5 years; however, given the mechanism of action of this intervention, benefits are very likely to accrue starting at the time of primary tooth eruption. Limited evidence found no clear effect on caries increment between performing a single fluoride varnish once every 6 months versus once a year or between a single application every 6 months versus multiple applications once a year or every 6 months.
Suggestions for Practice Regarding I StatementIn deciding whether to routinely perform screening examinations for dental caries in children from birth to age 5 years, clinicians should consider the following.
Potential Preventable BurdenDental caries is the most common chronic disease in children in the United States. It is four times more common than childhood asthma and seven times more common than hay fever. According to the NHANES, the prevalence of dental caries has risen from 24% to 28% between 1988–1994 and 1999–2004. Approximately 20% of surveyed children with caries had not received treatment. Symptomatic dental caries in children are associated with pain, loss of teeth, impaired growth, and decreased weight gain and can affect appearance, self-esteem, speech, and school performance. Dental-related concerns lead to the loss of more than 54 million school hours each year .
Potential HarmsNo studies examined the harms of performing primary care screening examinations for dental caries in children from birth to age 5 years. However, given the noninvasive nature of an oral examination, these harms are expected to be minimal.
Current PracticeIn one study, only about half of pediatricians reported examining the teeth of half of their patients ages 0 to 3 years.
Other Approaches to PreventionIn April 2013, the Community Preventive Services Task Force recommended fluoridation of community water sources based on strong evidence of effectiveness in reducing dental caries. It also recommends school-based dental sealant delivery programs to prevent caries. Xylitol may have promise as an additional method to reduce the risk for dental caries.
Xylitol is classified by the U.S. Food and Drug Administration as a dietary supplement and is found in over-the-counter consumer products such as wipes or gum. A single small, fair-quality trial of xylitol wipes use in children ages 6 to 35 months found a 91% relative reduction in decayed, missing, or filled surface increment. However, four other studies showed no clear effect of xylitol on caries risk in children younger than age 5 years. As such, there is currently not enough evidence to formally recommend its routine use in caries prevention.
ImplementationMany primary care providers already prescribe oral fluoride supplementation to patients with low levels of fluoride in their water; however, application of fluoride varnish is not currently commonly performed in many primary care offices (estimated at about 4% of practices in 2009). The techniques for application are simple and easy to learn, and fluoride varnish does not require specialized equipment or personnel and can be applied quickly. However, providers and other qualified staff may require some training before offering this procedure. Dentists and physicians can apply varnish in all states. In some states, physician assistants, nurse practitioners, nurses, and medical assistants can also do so.
Efforts are underway to address concerns surrounding resources, infrastructure, training, and payment mechanisms for the provision of fluoride varnish in the nondental primary care setting. For example, the AAP Section on Oral Health has partnered with the Health Resources and Services Administration's Maternal and Child Health Bureau and the ADA Foundation to educate and advocate for primary pediatric care professionals to apply fluoride varnish. They have created a Web site with a number of helpful tools and resources to assist nondental primary care providers, including how to acquire the materials required to provide varnish, as well as state-by-state information on billing codes and any training requirements (available at http://www2.aap.org/oralhealth/PracticeTools.html). The National Interprofessional Initiative on Oral Health, a consortium of funders and health professionals, focuses on educating and training primary care clinicians on oral health prevention (additional information available at http://www.niioh.org).
CostState Medicaid reimbursement for fluoride varnish application, when offered, ranges from $9 to $53 per application when applied by licensed providers who have had appropriate training, including physicians, physician assistants, nurse practitioners, registered nurses, and licensed practical nurses (varying by state).
Research Needs and GapsStudies are needed to assess and validate multivariate risk assessment tools that can accurately identify high-risk populations most likely to benefit from caries preventive interventions, such as fluoride varnish.
Further research would also be helpful to confirm the benefits of fluoride varnish among lower-risk and younger children.
Racial and ethnic minority children, as well as children living in low socioeconomic conditions, are at significantly increased risk for caries compared with white children and children who live in adequate to high socioeconomic conditions. Future studies on risk assessment and preventive interventions should enroll sufficient numbers of racial and ethnic minority children to understand the benefits and harms of interventions in these specific populations.
More research is also needed to estimate the effectiveness of interventions by clinicians to educate parents and caregivers about optimum health practices for oral hygiene at home.
No information available.
The AAP has issued two policy statements related to dental care in children. The first, issued in 2003 and reaffirmed in 2009, encourages providers to incorporate oral health–related services into their practices. Specifically, the AAP recommends an oral health assessment for all children by age 6 months and a first dental visit by age 1 year. The second statement supports oral fluoride supplementation and application of fluoride varnish in children “at risk” for dental caries. The ADA recommends that children be seen by a dentist within 6 months of eruption of the first tooth and no later than age 12 months. It also recommends the application of fluoride varnish every 6 months in preschool-aged children who are at “moderate” risk for dental caries and every 3 to 6 months in children who are at “high” risk. It recommends daily dietary fluoride supplements for children from birth to age 16 years who are at “high” risk for developing dental caries and whose primary source of drinking water is deficient in fluoride; “high risk” status can be determined using risk assessment tools developed by one of several professional health organizations. Dietary fluoride supplementation is not recommended when water fluoridation levels are greater than 0.6 ppm F. The Centers for Disease Control and Prevention recommend that clinicians counsel parents about appropriate use of fluoridated toothpastes, especially in children age 2 years and younger; prescribe fluoride supplements to children at high risk for dental caries whose drinking water lacks adequate fluoridation; and limit the use of high-concentration fluoride products, such as varnish and gel, to high-risk individuals. The American Academy of Pediatric Dentistry states that fluoride dietary supplements should be considered for children at risk for caries who drink fluoride-deficient (<0.6 ppm) water. It also states that children at increased risk for caries should receive a professional fluoride treatment (e.g., 5% sodium fluoride varnish or 1.23% acidulated phosphate fluoride) every 6 months. The American Academy of Family Physicians is updating its recommendations on the subject.