ASCO/ASTRO/AUA/SUFU Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer Guideline Summary

Design and created by Guideline Central in participation with the American Society for Radiation Oncology, American Society of Clinical Oncology, American Urological Association, and Society of Urodynamics Female Pelvic Medicine & Urogenital Reconstruction.

Document Overview

Document Title: Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer

Authoring Societies

American Society for Radiation Oncology

American Society of Clinical Oncology

American Urological Association

Society of Urodynamics Female Pelvic Medicine & Urogenital Reconstruction

Document Publication Date: Apr 26, 2017

Page Last Reviewed/Updated: May 6, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: www.ncbi.nlm.nih.gov/pmc/articles/PMC5626446/

Source Citation: Chang, S. S., Bochner, B. H., Chou, R., Dreicer, R., Kamat, A. M., Lerner, S. P., Lotan, Y., Meeks, J. J., Michalski, J. M., Morgan, T. M., Quale, D. Z., Rosenberg, J. E., Zietman, A. L., & Holzbeierlein, J. M. (2017). Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/ASTRO/SUO Guideline. The Journal of urology, 198(3), 552–559. https://doi.org/10.1016/j.juro.2017.04.086

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Document Objectives: This multi-disciplinary, evidence-based guideline for clinically non-metastatic muscle-invasive bladder cancer focuses on the evaluation, treatment, and surveillance of muscle-invasive bladder cancer guided toward curative intent.

Scope: Assessment and Screening, Management, Treatment

Diseases/Conditions (MeSH)

D011878 - Radiotherapy

D001749 - Urinary Bladder Neoplasms

D000072281 - Lymphadenopathy

D015653 - Cystectomy

D011878 - Radiotherapy

D001749 - Urinary Bladder Neoplasms

D000072281 - Lymphadenopathy

D015653 - Cystectomy

Keywords: Bladder Preservation, Non-Metastatic cancer, bladder cancer

Inclusion Criteria: Male, Female, Adolescent, Adult, Child, Older Adult

Health Care Settings: Hospital, Operating and Recovery Room, Outpatient, Radiology Services

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant, Radiology Technologist

Recommendation Development Processes & Methodology

Number of Source Documents: 331

Literature Search Start Date: Monday, January 1, 1990

Literature Search End Date: Monday, May 18, 2020

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: No