Lung Cancer Surveillance After Definitive Curative-Intent Therapy
Key Points
Key Points
Non-Small Cell Lung Cancer
The chance of NSCLC recurrence is greatest during the first 2 years following treatment with curative intent.
- Patients with an intrathoracic recurrence may be salvaged with surgical resection, stereotactic body radiotherapy (SBRT) or chemoradiation depending on the clinical scenario.
- Early identification of extra-thoracic metastatic recurrence may allow prompt molecular testing and facilitate the safe administration of precision palliative therapy before patients develop severe symptoms or deteriorate.
Two or more years after curative intent therapy, patients are at higher risk of developing a second primary lung cancer (1.5-2% per year) and may benefit from screening.
Small Cell Lung Cancer
- The risk of intracranial recurrence is significant. Therefore, close central nervous system (CNS) surveillance may afford treatment before permanent neurologic sequelae develop from symptomatic SCLC brain metastases.
Recommendations
...commendations
...ommendations apply to patients with curatively tre...
...undergo surveillance imaging for recu...
...should undergo surveillance imagi...
...inicians should use a diagnostic chest CT t...
...d use a low dose screening chest CT when c...
...ould NOT use FDG-PET/CT as a survei...
...aging may be omitted in patients who are clini...
...uld NOT use circulating biomarkers as a sur...
...NSCLC patients, clinicians should NOT use brain...
In patients who have undergone curative...