Treatment of Congenital Hemophilia A and B

Publication Date: June 19, 2024

Key Points

Key Points

  • Hemophilia is a congenital X-linked bleeding disorder that affects an estimated 1,125,000 individuals worldwide, 80% of whom have hemophilia A.
  • Individuals with severe (and some moderate) forms of hemophilia not treated with prophylaxis may experience spontaneous bleeding, of which the most frequent are joint and muscle bleeding.
  • Prophylaxis rather than episodic treatment is strongly recommended for severe and moderately-severe hemophilia A and B.

Treatment

...atment...

...hilia A Without Inhib...

...ls with severe and moderately-severe hemop...

...with severe and moderately-severe...

...duals with severe and moderately-severe hemophil...

...resource-limited settings in which the use of stan...

...eviously untreated individuals with severe...

...viduals with severe and moderately-...


...ia A With Inhibitors...

...ndividuals with severe hemophilia...

In individuals with severe hemophili...

...s with severe hemophilia A with hi...

...dividuals with severe hemophilia A...

...iduals with severe hemophilia A with inhibito...


...philia B Without Inhib...

...ith severe and moderately-severe hemophi...

...ith severe and moderately-severe hemophilia...