Interstitial Lung Disease in People With Systemic Autoimmune Rheumatic Disease

Publication Date: July 8, 2024

Key Points

Key Points

Guideline Summary:

  • This guideline provides evidence-based recommendations for the screening and treatment of Interstitial Lung Disease (ILD) in people with Systemic Autoimmune Rheumatic Diseases (SARDs) (Rheumatoid Arthritis [RA], Systemic Sclerosis [SSc], Idiopathic Inflammatory Myositis [IIM including polymyositis, dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy], Mixed Connective Tissue Disease [MCTD], and Sjögren’s Disease [SjD]) associated with the greatest risk of ILD, and for monitoring for ILD progression.

Screening and Monitoring

...reening and Monito...

.... Risk Factors for the Development...


Table 3. Summary of Recommendations for...

Recommendation...

...ple with SARDsa at increased risk of...

...ople with SARDs at increased risk of developin...

...SARDs at increased risk of developing ILD,...

...th SARDs at increased risk of deve...

...with SARDs at increased risk of devel...

...SARDs at increased risk of developing IL...

...ith SARDs at increased risk of developing...

...SARDs at increased risk of developing...


.... Summary of Recommendations for Monitoring for I...

...commendations...

...th SARDs-ILD, we conditionally recommend monitori...

...with SARDs-ILD, we conditionally recomm...

...people with SARDs-ILD, we conditio...

...people with SARDs-ILD, we conditionally rec...

...th SARDs-ILD, we conditionally recommend agains...

...people with SARDs-ILD, we condition...

...or people with SARDs-ILD, we conditio...

...ith IIM-ILD and SSc-ILD, we suggest PFTs for m...

...r people with RA-ILD, SjD-ILD, and MCT...

...ith SARDs-ILD, we do not provide guidance about f...

...eople with SARDs-ILD, we suggest assessmen...


...Recommendations for ILD Screening and...


...re 2. Interstitial Lung Disease Screen...


Treatment

...atment...

...Summary of Recommendations for Management of SAR...

...ommendations...

...le with SARD-ILD other than SSc-ILD, we condit...

...h SSc-ILD, we strongly recommend agains...

...with SARD-ILD, we conditionally recommen...

...people with SSc-ILD and MCTD-ILD, we c...

...people with SARD-ILD, we condition...

...or people with SSc-ILD, we conditionally recom...

For people with SjD-ILD, IIM-ILD, and...

...RA-ILD, the Panel was not able to come to co...

...with SARD-ILD, we conditionally reco...

...with SARD-ILD receiving mycophenolate without ev...

...with SARD-ILD, we conditionally re...

...with IIM-ILD, we conditionally recommend JAK in...

...e with SARD-ILD other than IIM-ILD, we c...

...or people with IIM-ILD, we conditio...

...ople with SARD-ILD other than IIM-ILD, we co...

...people with SARD-ILD, we conditionally recomm...

...people with SARD-associated ILD, we c...


...ble 6. Recommendations for Management of SARD-IL...

...mendations...

...ecommend against using long-term glucocorticoi...

...her SARD-ILD we conditionally recommend...

...eople with SARD-ILD progression despite first...

...ith RA-ILD progression despite firs...

...eople with SARD-ILD, other than RA-ILD, progre...

...h SSc-ILD, MCTD-ILD, RA-ILD progressio...

...ith SjD-ILD and IIM-ILD progression despi...

...ople with IIM-ILD progression despite...

...h SARD-ILD, other than IIM-ILD, progression despit...

...IIM-ILD progression despite first ILD t...

...IIM-ILD and MCTD-ILD progression despite...

...e with SARD-ILD progression despite first ILD tre...

...ith SSc-ILD progression despite first ILD t...


...al Treatment Options for the Treatment of Inte...


...mendations for Management of SARD-ILD Progress...


...7. Recommendations for Management o...

...commendation...

...eople with SARD and RP-ILD, we conditionally rec...

...r people with SARD and RP-ILD, we conditionall...

...SARD and RP-ILD, we conditionally r...

...RP-ILD, we conditionally recommen...

...eople with SARD and RP-ILD, we condi...

For people with SARD and RP-ILD, we conditiona...


...5. Recommendations for Management of SARD With RP-...