Biomarkers for Adjuvant Endocrine and Chemotherapy in Early-Stage Breast Cancer
Key Points
Key Points
Diagnosis
Diagno...
...Diagnosed ER-positive, HER2-negative Breast C...
...ype DX (21-gene recurrence score)...
...commendation 1.1If a patient has node-nega...
...ommendation 1.2In the group of pat...
...endation 1.3In the group of patients in Recommend...
Recommendation 1.4If a patient is...
...ndation 1.5In the group of patients in Rec...
...n 1.6If a patient is premenopausal an...
...on 1.7If a patient has node-positive breast cance...
...t (70-gene signature)...
Recommendation 1.8If a patient is older than 50...
...tion 1.9If a patient is 50 years of age or youn...
...ion 1.10If a patient has low clinical ris...
...1.11If a patient has node-positive breast cancer...
...edict (12-gene risk score)...
...commendation 1.12If a patient is postmenopausal...
...ecommendation 1.13If a patient is preme...
...mendation 1.14If a patient has breast cancer...
...igna (PAM50...
...ommendation 1.15If a patient is postmenopausa...
...ecommendation 1.16If a patient is premeno...
...tion 1.17If a patient is postmenopausal and...
...endation 1.18If a patient has node-positive breast...
...mmostra...
...ficient evidence to recommend use of Mammos...
Breast Cancer Index (...
...a patient has ER-positive, HER2-negative,...
...atient has ER-positive, HER2-negativ...
Ki67
...ation 1.19If a patient is postmenop...
...on 1.20If a patient is postmenopausal and has brea...
...ion 1.21Despite the limitations associated with Ki...
...stochemistry 4 (IHC4)...
...1.22If a patient has node-negative or nod...
...and PAI-1...
...t has ER-positive, HER2-negative (nod...
...nt has HER2-positive breast cancer or trip...
...ocrine Therapy For ER Receptor-positive HER2-ne...
...DX, EndoPredict, Prosigna, Ki67, or...
...ecommendation 1.23If a patient has node-negative...
BCI
...tion 1.24If a patient has node-negative or...
...1.25If a patient has node-positive...
...linical Treatment Score post-5 Year...
...ion 1.26If a patient is postmenopausa...
...ive Breast Cancer or TNBC...
...cotype DX, EndoPredict, MammaPrint, BCI, Pros...
...ation 1.27If a patient has HER2-positiv...
Emerging Biomark...
...or-Infiltrating Lymphocytes (TIL...
...n 1.28If a patient has node-negative...
...1 Testing
...tion 1.29If a patient has node-negative or n...
Circulating Tumor Ce...
...1.30If a patient has node-negative or...
...ng Tumor DNA (ctDNA)...
...endation 1.31If a patient has node-negative...
...able 1. Breast Cancer Biomarkers to Guide Adju...
...thm on Biomarkers to Guide Decisions on Adjuvan...
...fication of Patients According to Clinical Ris...
...ASCO believes that cancer clinical t...