Treatment of Early-Stage Colorectal Cancer

Publication Date: February 25, 2019

Key Points

Key Points

Historically, some of the highest incidence rates for colorectal cancers have been in “more developed” regions. However, approximately 45% of these occur in “less developed” regions, representing 9-10% of cancers in those populations.

Since different regions of the world, both among and within countries, differ with respect to resource access, ASCO has established a process for stratifying guidelines according to resource availability (basic, limited, enhanced and maximal – See Table 1). This framework emphasizes that variations occur not only between but also within countries—for example, between rural and urban areas.

Treatment

...eatment

...ework of Resource StratificationHav...


...metastatic, non-obstructing colon cancer Colon C...

...with non-obstructing, resectable,...

...h non-obstructing, resectable, local...

...ith non-obstructing, resectable, loca...


...Cancer Stages IIB-IIC: T4N0 (Non-o...

...non-obstructing, locally advanced (i...

...th non-obstructing, locally advanc...

...ents with non-obstructing, locally adv...

...s with non-obstructing, locally advanced (ie., wi...

...ients with non-obstructing, locally advanced (ie.,...

...atients with non-obstructing, locally advanced (ie...

...n-obstructing, resectable, locally advanced (ie....


...le 4. Colon Cancer Stages IIB-IIC: T3N0 Obstru...

...obstructing, locally advanced (ie., with inva...

...ith obstructing, locally advanced (ie., with invas...

...tients with obstructing, locally advan...

...th obstructing, locally advanced (ie., with i...

Patients with obstructing, locally advanc...


...e 5. High-Risk Obstructing Colon Cancer...

...tients with obstructing, locally advanced (i...

Patients with high-risk, obstructing stage II...

...h high risk, obstructing stage III...


...tal Cancer Stage I– clinical stage T1 N0...

...nts with nonmetastatic cT1N0 rectal canc...

...ts with nonmetastatic cT1N0 rectal cancerEn...

...select low risk (cT1N0 without adverse features li...


Table 7. Rectal Cancer Stage I– clinical...

...nmetastatic cT2N0 rectal cancerBasic and...

...th nonmetastatic cT2N0 rectal cance...

...with nonmetastatic cT2N0 rectal cancerMaximal...


...tal Cancer Stage IIA– clinical stage T3 N0...

...h clinically resectable cT3N0 rectal ca...

...nts with clinically resectable cT3N0 rectal c...

...ts with clinically resectable cT3N...

...th clinically resectable cT3N0 rec...

...s with clinically resectable cT3N0 rectal can...

...linically resectable cT3N0 rectal cancerEnhan...

...tients with clinically resectable pT3N0 rec...

...clinically resectable cT3N0 rectal canc...

...th clinically resectable cT3N0 rectal cancer, hi...


...9. Early-Stage Colon Cancer Post-Trea...

...ients with Stage II CRCBasic Medical h...

...ted patients with Stage II CRCLimited Medica...

...ents with Stage II CRC at standard riskEnhanced...

...atients with Stage II CRC at high riskEnhanced...

...patients with Stage II CRC at standard an...


...ly-Stage Rectal Cancer Post-Treatment S...

...ted patients with rectal cancerBasic Me...

...nts with rectal cancer at standard riskLimi...

...s with rectal cancer at high riskEnhanced and...

...ts with rectal cancer who have not...

...d patients with rectal cancer at st...

...tients with rectal cancer at standard ris...

...reated patients with rectal cancer at high risk wh...

...d patients with rectal cancer, wher...

...s with rectal cancer at high risk who have not r...


Table 11. Early-Stage Colon Cancer...


...-Stage Rectal Cancer Follow Up (sum...