Antiemetics

Publication Date: July 13, 2020

Key Points

Key Points

  • The development of increasingly effective antiemetic regimens over the last quarter century has greatly reduced the incidence of nausea and vomiting due to chemotherapy.
  • The recommended approach to preventing nausea and vomiting varies by the emetic risk of the treatment regimen.
  • Adherence to antiemetic guidelines has been linked with improved control of nausea and vomiting.
  • This update of the 2017 guideline adds guidance on the use of dexamethasone as a prophylactic antiemetic in patients receiving checkpoint inhibitors (CPIs).

Treatment

Treatm...

...dult Patien...

...t patients, the addition of a checkpo...

...Risk Antineoplastic Agents...

...tients treated with cisplatin and ot...

...tients treated with an anthracycline c...

...Emetic-Risk Antineoplastic Agents...

...treated with carboplatin area under...

...reated with moderate-emetic-risk antineopl...

...ult patients treated with cyclophosp...

...etic-Risk Antineoplastic Agents

...ients treated with low-emetic-risk antineopl...

...inimal Emetic Risk Antineoplastic Agents

...atients treated with minimal emetic...

...ntineoplastic Combinations...

...atients treated with antineoplastic...

...nctive Drugs...

...useful adjunct to antiemetic drugs, but i...

...abinoids...

...idence remains insufficient for a rec...

...mentary and Alternative Ther...

...insufficient for a recommendation for or...

...therapy With Stem-Cell or Bone Marrow Transpl...

...dult patients treated with high-dose...

(New) A four-drug combination of an...

...ntineoplastic Therapy...

...treated with multiday antineoplasti...

...ult patients treated with 4- or 5-da...

...through Nausea and Vomiti...

...patients with breakthrough nausea or vomiting, cli...

...t patients who experience nausea or vomiting desp...

...abinol and nabilone ( IC , I , M )6539...

...( IC , L , M )6539...

...ticipatory Nausea and Vomiting...

...uld receive the most active antiemetic regimen...

...c Risk Radiation Therapy...

...tients treated with high-emetic-risk radiatio...

...Emetic Risk Radiation Therapy...

...reated with moderate-emetic-risk radiation t...

...Emetic Risk Radiation Therapy...

...ult patients treated with radiation therap...

...nimal Emetic Risk Radiation Therap...

...nts treated with minimal emetic risk radiation...

...rent Radiation and Antineoplastic Agent Thera...

...treated with concurrent radiation and antineoplas...


...ediatric Pat...

...metic Risk Antineoplastic Agent...

...) Pediatric patients treated with hi...

...Pediatric patients treated with high-emetic-risk...

...ed) Pediatric patients treated with high-...

...ic Risk Antineoplastic Agents...

...atric patients treated with moderate-...

...atric patients treated with moderate-emetic-risk a...

...tic Risk Antineoplastic Agents...

...ediatric patients treated with low-emetic-r...

...Emetic Risk Antineoplastic Ag...

...ic patients treated with minimal emetic risk antin...


...Risk of Single Intravenous Antineoplastic Agents...


...metic Risk of Single Oral Antineoplast...


...able 3. Antiemetic Dosing for Adult...


...4. Emetic Risk in Adults by Site of Radiatio...


...able 5. Antiemetic Administration in Adults by Ra...