Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies.

Publication Date: 2024 May 08


Full Text Sources

Elsevier Science

Related Articles


Authors

Leonardo Martinez; James A Seddon; C Robert Horsburgh; Christoph Lange; Anna M Mandalakas

Abstract

OBJECTIVE

Tuberculosis is a preventable disease. However, there is debate regarding which individuals would benefit most from tuberculosis preventive treatment and whether these benefits vary in settings with a high burden and low burden of tuberculosis. We aimed to compare the effectiveness of tuberculosis preventive treatment in exposed individuals of differing ages and Mycobacterium tuberculosis infection status while considering tuberculosis burden of the settings.


Source

The Lancet. Respiratory medicine


Pub Types(s)

Journal Article


Language

English


PubMed ID

38734022