Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients. Journal Abstract

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.

Publication Date: 2024 Aug 19

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Authors

Adriane Halik; Marlon Tilgner; Patricia Silva; Natalia Estrada; Robert Altwasser; Ekaterina Jahn; Michael Heuser; Hsin-An Hou; Marta Pratcorona; Robert K Hills; Klaus H Metzeler; Laurene Fenwarth; Anna Dolnik; Christine Terre; Klara Kopp; Olga Blau; Martin Szyska; Friederike Christen; Jan Krönke; Loïc Vasseur; Bob Löwenberg; Jordi Esteve; Peter J M Valk; Matthieu Duchmann; Wen-Chien Chou; David C Linch; Hartmut Döhner; Rosemary E Gale; Konstanze Döhner; Lars Bullinger; Kenichi Yoshida; Frederik Damm

Abstract

OBJECTIVE

Deletions and partial losses of chromosome 7 (chr7) are frequent in acute myeloid leukemia (AML) and are linked to dismal outcome. However, the genomic landscape and prognostic impact of concomitant genetic aberrations remain incompletely understood.

Source

Journal of hematology & oncology

Pub Types(s)

Journal Article

Language

English

PubMed ID

39160538