Treatment Of Idiopathic Pulmonary Fibrosis
Publication Date: July 1, 2015
Key Points
Key Points
- Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrosing interstitial pneumonia of unknown cause occurring in adults.
- Radiologic and/or histopathologic patterns are consistent with usual interstitial pneumonia.
- Significant advances have been recently made in the clinical management of IPF.
- All of the recommendations in favor of treatment are conditional, meaning that decisions to treat patients with IPF should be individualized. Clinicians should be cautious to not interpret recommendations with the same grade as having the same net effects.
- The recommendations in favor of treatment put a higher value on the potential benefit of patient-important outcomes such as disease progression as measured by FVC decline and mortality and a lower value on potentially significant adverse effects and the cost of treatment.
Treatment
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...with IPF, the guideline committee recommends:...
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...se warfarin anticoagulation in patients...
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...ians NOT use ambrisentan, a selective ER-...
...atients with IPF, the guideline committ...
...nicians use nintedanib. ( Moderate , C, M...
...use pirfenidone. ( Moderate , C, M)695...
...ians NOT use sildenafil, a phosphodieste...
...ns NOT use bosentan or macitentan, bot...
...NOT use N-acetylcysteine monother...
...nicians use regular anti-acid trea...