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Antimicrobial Prophylaxis in Surgery GUIDELINES Pocket Guide

Approved By

American Society of Health-System Pharmacists

Infectious Diseases Society of America

Society for Healthcare Epidemiology of America

Surgical Infection Society

The Antimicrobial Prophylaxis in Surgery GUIDELINES Pocket Guide is endorsed by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, The Society for Healthcare Epidemiology of America, and the Surgical Infection Society. It contains National Healthcare Safety Network definitions of wound infection, general recommendations for prophylaxis such as weight-based dosing, duration of treatment, and the management of colonization with Staphylococcus aureus.  Comprehensive tables detail antimicrobial adult and pediatric doses, redosing intervals, choices by procedure, and alternatives in cases of β-lactam allergy.


  • Spiral Bound
  • 16 pages
  • 80# Diamond Silk Cover with Satin Aqueous Coating
  • 4.5″ x 7.25″
  • Key Points
  • Definitions
  • Treatment Recommendations
    • Weight-based dosing
    • Duration
    • Colonization
  • Tables
    • Recommended Doses and Redosing Intervals
      • Adult dose
      • Pediatric dose
      • Adult half-life
    • Antimicrobial Recommendations by Procedure
      • Alternatives in β-lactam allergy

The American Society of Health-System Pharmacists (ASHP) develops official professional policies, in the form of policy positions and guidance documents, in order to establish best practices and provide guidance to ASHP members and other audiences impacted by health-system pharmacy practice. For more than 70 years, ASHP has helped pharmacists who practice in hospitals and health systems improve medication use and enhance patient safety.

The Infectious Diseases Society of America (IDSA) represents physicians, scientists and other health care professionals who specialize in infectious diseases. IDSA's purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases.

SHEA is dedicated to advancing the science and practice of healthcare epidemiology and preventing and controlling morbidity, mortality, and the cost of care linked to healthcare-associated infections. The society partners with epidemiologists, infectious disease practitioners, basic scientists, public health specialists, consumers, policymakers, and others, to achieve better healthcare outcomes.

The Surgical Infection Society is committed to providing leadership in the prevention, diagnosis and treatment of infection in surgical patients. The mission of the Society is to educate health care providers and the public about infection in surgical patients and promote research in the understanding, prevention and management of surgical infections.

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(407) 878-7606

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