Cushing’s Syndrome Treatment

Published: August 2015
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  • Key Points 
  • Treatment Goals for Cushing’s Syndrome 
  • Optimal Adjunctive Management 
  • First-line Treatment Options 
  • Remission and Recurrence After Surgical Tumor Resection
  • Second-line Therapeutic Options
  • Repeat Transsphenoidal Surgery
  • Radiation Therapy/Radiosurgery for Cushing's Disease 
  • Medical Rx
  • Special Populations/Considerations
  • Approach for Long-term Follow-up
  • Figure 
    • Suggested Algorithm for the Treatment of Cushing’s Syndrome 
  • Table 
    • Medical Treatment of Cushing’s Syndrome
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Founded in 1916, The Endocrine Society is the world's oldest, largest, and most active organization devoted to research on hormones and the clinical practice of endocrinology. The Society works to foster a greater understanding of endocrinology amongst the general public and practitioners of complementary medical disciplines and to promote the interests of all endocrinologists at the national scientific research and health policy levels of government. The Hormone Foundation, the Society's public education affiliate, is a leading source of hormone-related health information for the public, physicians, allied health professionals and the media.


This pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.


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