Immune-related Adverse Events from Immune Checkpoint Inhibitor Therapy

Published: November 2021
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  • Key Points
  • Key Recommendations
  • Tables
    • Immunosuppressive Agents
    • Commonly Conducted Testing at Baseline Prior to ICPi Therapy
    • Commonly Conducted Testing During irAE Management With Steroids
    • Cutaneous Toxicities
    • Gastointestinal Toxicities
    • Lung Toxicities
    • Endocrine Toxicities
    • Musculoskeletal Toxicities
    • Renal Toxicities
    • Nervous System Toxicities
    • Hematologic Toxicities
    • Cardiovascular Toxicities
    • Ocular Toxicities
    • Systemic Toxicities
    • Prevention and Management of Adverse Events Related to Steroid Use
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Founded in 1964, the American Society of Clinical Oncology is the world's leading professional organization for physicians and oncology professionals caring for people with cancer.


This pocket guide is derived from recommendations in the American Society of Clinical Oncology Guideline. This resource is a practice tool based on ASCO® practice guidelines and is not intended to substitute for the independent professional judgment of the treating physician. Practice guidelines do not account for individual variation among patients. This pocket guide does not purport to suggest any particular course of medical treatment. Use of the practice guidelines and this resource are voluntary. The practice guidelines and additional information are available at Copyright © 2021 by American Society of Clinical Oncology. All rights reserved.


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