Nutrition Support of Neonatal Patients at Risk for Metabolic Bone Disease
Publication Date: May 17, 2017
Last Updated: March 14, 2022
Recommendations
Maternal vitamin D deficiency is a risk factor for neonatal vitamin D deficiency and abnormal bone health, and we suggest that pregnant women be screened for vitamin D deficiency and those that are deficient be supplemented. (W)
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Insufficient data are available to determine the effect of maternal magnesium sulfate and folic acid use on neonatal bone health. (FR)
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When available, we suggest human milk with nutrient fortifier for the preterm infant. (W)
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When human milk is not available, we suggest that nutrient-enriched formula be used. (W)
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We suggest vitamin D supplementation for healthy breastfed infants and those with malnutrition and/or rickets. ()
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Further studies are needed to determine the optimal dose, route, and duration of supplementation in each of these conditions. (FR)
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We suggest that PN predisposes the infant to metabolic bone disease. (W)
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We suggest the use of PN solutions with high-dose calcium and phosphorus supplementation. (W)
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PN containing aluminum is a risk factor for metabolic bone disease of the neonate, and we suggest that future efforts be made to reduce aluminum content of PN. (S)
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Recommendation Grading
Overview
Title
Nutrition Support of Neonatal Patients at Risk for Metabolic Bone Disease
Authoring Organization
American Society for Parenteral and Enteral Nutrition
Publication Month/Year
May 17, 2017
Last Updated Month/Year
January 17, 2024
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Inclusion Criteria
Female, Male, Infant
Health Care Settings
Hospital
Intended Users
Dietician nutritionist, nurse, nurse practitioner, physician, physician assistant
Scope
Management
Diseases/Conditions (MeSH)
D018529 - Nutritional Support, D001851 - Bone Diseases, Metabolic
Keywords
enteral nutrition, parenteral nutrition, metabolic bone disease, Nutrition Support