Sequential Organ Failure Assessment (SOFA) Score

Predicts ICU mortality based on lab results and clinical data.

System of Measurement

Partial Pressure of Oxygen (mm Hg) (kPa)

Fraction of Inhaled O₂ (%) (%)

Platelet Count (×10³/µL) (×10⁹/L)

Glasgow Coma Scale (points) (points)

Bilirubin (mg/dL) (µmol/L)

Level of Hypotension (Vasopressor Status For ≥ 1 Hr)

No Hypotension

MAP < 70

On vasopressors, dopamine < 5 µg/kg/min or dobutamine (any dose)

Dopamine > 5 µg/kg/min or Epi/Norepi < 0.1 µg/kg/min

Dopamine > 15 µg/kg/min or Epi/Norepi > 0.1 µg/kg/min

Creatinine (or Urine Output, Use Worst Value)

Cr < 1.2 mg/dL (< 106 µmol/L)

Cr 1.2-1.9 mg/dL (106-168 µmol/L)

Cr 2.0-3.4 mg/dL (177-301 µmol/L)

Cr 3.5-4.9 mg/dL (309-433 µmol/L) or Urine Output < 500ml/day

Cr > 5.0 mg/dL (> 442 µmol/L)

Interpretation

Source: Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. In: Vol 22. 1996:707–710.