ACG Management of Crohn’s Disease in Adults Guideline Summary - Guideline Central

Design and created by Guideline Central in participation with the American College of Gastroenterology.

Document Overview

Document Title: Management of Crohn’s Disease in Adults

Authoring Society: American College of Gastroenterology

Document Publication Date: Mar 1, 2018

Page Last Reviewed/Updated: May 5, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: gi.org/guideline/management-of-crohns-disease-in-adults/

Source Citation: Lichtenstein, Gary R MD, FACG; Loftus, Edward V MD, FACG; Isaacs, Kim L MD, PhD, FACG; Regueiro, Miguel D MD, FACG; Gerson, Lauren B MD, MSc, MACG (GRADE Methodologist); Sands, Bruce E MD, MS, FACG. ACG Clinical Guideline: Management of Crohn's Disease in Adults, American Journal of Gastroenterology: April 2018 - Volume 113 - Issue 4 - p 481-517 doi: 10.1038/ajg.2018.27

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Document Objectives: The purpose of this guideline is to review Crohn's disease clinical features and natural history, diagnostics, and therapeutic interventions.

Scope: Assessment and Screening, Diagnosis, Management, Treatment

Diseases/Conditions (MeSH)

D001327 - Autoimmune Diseases

D007166 - Immunosuppressive Agents

D003424 - Crohn Disease

D015212 - Inflammatory Bowel Diseases

D015212 - Inflammatory Bowel Diseases

D003424 - Crohn Disease

D007166 - Immunosuppressive Agents

D001327 - Autoimmune Diseases

Keywords: Crohn's disease, autoimmune disease, autoinflammatory, inflammatory bowel disease

Target Patient Population: Patients with Crohn disease

Inclusion Criteria: Female, Male, Adolescent, Adult, Child, Older Adult

Health Care Settings: Ambulatory, Hospital, Outpatient

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Supplemental Methodology Resource: Data Supplement

Number of Source Documents: 375

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: No