AHA Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies Guideline Summary - Guideline Central

Design and created by Guideline Central in participation with the American Heart Association.

Document Overview

Document Title: Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies

Authoring Society: American Heart Association

Document Publication Date: Apr 16, 2019

Page Last Reviewed/Updated: May 5, 2026

Document Type: Other

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000664

Source Citation: Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association
Janani Rangaswami, MD, Vice Chair Vivek Bhalla, MD, FAHA John E.A. Blair, MD Tara I. Chang, MD, MS Salvatore Costa, MD Krista L. Lentine, MD, PhD Edgar V. Lerma, MD, FAHA Kenechukwu Mezue, MD, MSc Mark Molitch, MD Wilfried Mullens, MD, PhD Claudio Ronco, MD W.H. Wilson Tang, MD, FAHA Peter A. McCullough, MD, MPH, FAHA, Chair On behalf of the American Heart Association Council on the Kidney in Cardiovascular Disease and Council on Clinical Cardiology

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Document Objectives: To describe the epidemiology and pathogenesis of cardiorenal syndrome in the context of the continuously evolving nature of its clinicopathological description over the past decade.

Scope: Diagnosis, Treatment

Diseases/Conditions (MeSH)

D058186 - Acute Kidney Injury

D058186 - Acute Kidney Injury

Keywords: chronic kidney disease, heart failure

Inclusion Criteria: Female, Male, Adult, Older Adult

Health Care Settings: Ambulatory, Hospital

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Supplemental Methodology Resource: Data Supplement

Number of Source Documents: 290

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: No