NSGC Identification Of Individuals At Risk For Lynch Syndrome Using Targeted Evaluations And Genetic Testing Guideline Summary - Guideline Central

Design and created by Guideline Central in participation with the National Society of Genetic Counselors.

Document Overview

Document Title: Identification Of Individuals At Risk For Lynch Syndrome Using Targeted Evaluations And Genetic Testing

Authoring Society: National Society of Genetic Counselors

Document Publication Date: Aug 1, 2012

Page Last Reviewed/Updated: May 5, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: onlinelibrary.wiley.com/doi/10.1007/s10897-011-9465-7

Source Citation: https://doi.org/10.1007/s10897-011-9465-7

Document Scope, Criteria, and Use Cases

Document Objectives: The purpose of this practice guideline is to provide guidance and a testing algorithm for Lynch Syndrome as well as recommendations on when to offer testing.

Scope: Assessment and Screening, Counseling, Prevention

Diseases/Conditions (MeSH)

D005820 - Genetic Testing

D003123 - Colorectal Neoplasms, Hereditary Nonpolyposis

D055847 - Lynch Syndrome II

D005823 - Genetics

D005817 - Genetic Counseling

D053843 - DNA Mismatch Repair

D040941 - Heredity

D055847 - Lynch Syndrome II

D003123 - Colorectal Neoplasms, Hereditary Nonpolyposis

D005820 - Genetic Testing

D005823 - Genetics

D005817 - Genetic Counseling

D053843 - DNA Mismatch Repair

D040941 - Heredity

Keywords: Lynch syndrome, Mismatch repair, colorectal cancer, genetic counseling

Target Patient Population: Patients with risk of Lynch Syndrome

Inclusion Criteria: Female, Male, Adolescent, Adult, Older Adult

Health Care Settings: Ambulatory, Laboratory Services, Outpatient

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Number of Source Documents: 56

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: No

Grades quality of strength of recommendation?: No

Includes benefits/harms analysis with recommendations?: No