SCCM Insulin Infusion For The Management Of Hyperglycemia In Critically Ill Patients Guideline Summary - Guideline Central
Recommendations
Document Overview

Insulin Infusion For The Management Of Hyperglycemia In Critically Ill Patients

Society of Critical Care Medicine


Publication Date: Dec 1, 2012

Page Last Updated: May 5, 2026

Grading System

Quality of Evidence
Description of EvidenceHigh QualityModerate QualityLow QualityVery Low Quality
  • Well-performed RCTs
  • Very strong evidence from unbiased observational studies
  • RCTs with some limitations
  • Strong evidence from unbiased observational studies
  • RCTs with serious flaws
  • Some evidence from observational studies
  • Unsystematic clinical observations
  • Very indirect evidence from observational studies
Strength of Recommendation
Strong (1): "ES recommends..."
Benefits clearly outweigh harms and burdens or vice versa		1-H1-M1-L1-VL
Conditional (2): "ES suggests..."
Benefits closely balanced with harms and burdens		2-H2-M2-L2-VL
Ungraded Good Practice StatementUGPS

Document Overview

Document Title
Insulin Infusion For The Management Of Hyperglycemia In Critically Ill Patients
Authoring Society

Society of Critical Care Medicine

Document Publication Date
Dec 1, 2012
Page Last Reviewed/Updated
May 5, 2026
Document Type
Guideline
Country of Publication
United States
Full Text Freely Available
Yes
Full Text Guideline
journals.lww.com/ccmjournal/Fulltext/2012/12000/Guidelines_for_the_use_of_an_insulin_infusion_for.19.aspx
Source Citation

Critical Care Medicine: December 2012 - Volume 40 - Issue 12 - p 3251-3276
doi: 10.1097/CCM.0b013e3182653269

Document Scope, Criteria, and Use Cases

Document Objectives
To evaluate the literature and identify important aspects of insulin therapy that facilitate safe and effective infusion therapy for a defined glycemic end point.
Scope
Management, Treatment
Diseases/Conditions (MeSH)

D007328 - Insulin

D061385 - Insulins

D016638 - Critical Illness

D003422 - Critical Care

D006943 - Hyperglycemia

D020158 - Hyperglycinemia, Nonketotic

D003422 - Critical Care

D016638 - Critical Illness

D061385 - Insulins

D007328 - Insulin

D006943 - Hyperglycemia

D020158 - Hyperglycinemia, Nonketotic

Keywords
critical care, critical illness, hyperglycemia, insulin
Target Patient Population
Critical ill patients with hyperglycemia
Inclusion Criteria
Female, Male, Adolescent, Adult, Child, Older Adult
Health Care Settings
Emergency Care, Home Health, Hospital
Intended Users
Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Supplemental Methodology Resource
Data Supplement
Number of Source Documents
222
Includes peer/external review process?
Yes
Includes public comment process?
No
Methodologist involvement?
Yes
Patient involvement?
No
Includes multi-disciplinary group?
Yes
Includes systematic review?
Yes
Grades quality of strength of evidence?
Yes
Grades quality of strength of recommendation?
Yes
Discloses funding source?
Yes
Discloses conflicts of interest?
Yes
Includes benefits/harms analysis with recommendations?
Yes
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