AMP Validation of Next-Generation Sequencing-Based Oncology Panels Guideline Summary - Guideline Central

Design and created by Guideline Central in participation with the Association for Molecular Pathology.

Document Overview

Document Title: Validation of Next-Generation Sequencing-Based Oncology Panels

Authoring Society: Association for Molecular Pathology

Endorsing Society: College of American Pathologists

Document Publication Date: May 1, 2017

Page Last Reviewed/Updated: Dec 10, 2025

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: jmd.amjpathol.org/article/S1525-1578(17)30025-9/fulltext

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Scope: Diagnosis, Management, Prevention, Treatment

Diseases/Conditions (MeSH): D008495 - Medical Oncology

Keywords: Amplification-based NGS, Hybrid capture NGS, NGS, Oncology Panels, Sequencing

Inclusion Criteria: Female, Male, Adolescent, Adult, Older Adult

Health Care Settings: Ambulatory, Radiology Services

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant, Radiology Technologist

Recommendation Development Processes & Methodology

Number of Source Documents: 139

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: No

Grades quality of strength of recommendation?: No

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: No