Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease

Authoring Organization

Publication Month/Year

May 28, 2021

Last Updated Month/Year

August 15, 2023

Document Type


External Publication Status


Country of Publication


Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Ambulatory, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Treatment, Management

Diseases/Conditions (MeSH)

D015212 - Inflammatory Bowel Diseases, D003424 - Crohn Disease, D005402 - Fistula, D005747 - Gastric Fistula, D007412 - Intestinal Fistula


inflammatory bowel disease, Crohn's disease, IBD, crohns disease, fistulas, fistulizing

Source Citation

Feuerstein JD, Ho EY, Shmidt E, Singh H, Falck-Ytter Y, Sultan S, Terdiman JP; American Gastroenterological Association Institute Clinical Guidelines Committee. AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. Gastroenterology. 2021 Jun;160(7):2496-2508. doi: 10.1053/j.gastro.2021.04.022. PMID: 34051983.

Supplemental Methodology Resources

Technical Review