ISHLT Perioperative Use of ECLS in Lung Transplantation: Part III: Postoperative Considerations Guideline Summary - Guideline Central
Summary of Recommendations
Document Overview

Perioperative Use of ECLS in Lung Transplantation: Part III: Postoperative Considerations

International Society for Heart and Lung Transplantation


Publication Date: Jun 2, 2025

Page Last Updated: May 6, 2026

Class and Levels of Evidence

ClassDescription
IEvidence and/or general agreement that a given treatment, procedure, or technique is beneficial, useful and effective as applied to patients, clinicians, or researchers
IIaConflicting evidence and/or divergence of opinion about the usefulness/efficacy of the treatment, procedure, or technique; Weight of evidence/opinion is in favor of usefulness/efficacy
IIbConflicting evidence and/or divergence of opinion about the usefulness/efficacy of the treatment, procedure, or technique; Usefulness/efficacy is less well established by evidence/opinion
IIIEvidence or general agreement that the treatment, procedure, or technique is not useful or effective and in some cases may be harmful.
LevelDescription
AData derived from multiple, high-quality randomized clinical trials, meta-analyses of high-quality RCTs, or one or more RCTs corroborated by high-quality registry studies
B1Data derived from a single or multiple moderate-quality randomized clinical trial(s), meta-analyses of moderate-quality RCTs, or large nonrandomized studies; Data derived from a single or multiple moderate-quality randomized clinical trial(s), meta-analyses of moderate-quality RCT
B2Data derived from a single or multiple moderate-quality randomized clinical trial(s), meta-analyses of moderate-quality RCTs, or large nonrandomized studies; Data derived from one or more high-quality non-randomized, observational, or registry studies
C1Expert opinion supported by small, observational studies, retrospective studies, meta-analyses of such studies, or physiologic/mechanistic studies
C2Expert opinion alone or with group communications/questionnaires

Document Overview

Document Title
Perioperative Use of ECLS in Lung Transplantation: Part III: Postoperative Considerations
Authoring Society

International Society for Heart and Lung Transplantation

Document Publication Date
Jun 2, 2025
Page Last Reviewed/Updated
May 6, 2026
Document Type
Consensus Statement
Country of Publication
Global
Full Text Freely Available
Yes
Full Text Guideline
www.ishlt.org/docs/default-source/standards-guidelines/2025_consensusdocument_perioperativeuseofecls_postoperativeconsiderations.pdf?sfvrsn=8923878d_1
Source Citation

Archer Kilbourne Martin, Olaf Mercier, Brandi Bottiger, Marcelo Cypel, Julien Fessler, David Gomez-De-Antonio, Bronwyn Levvey, Haifa Lyster, Basil Nasir, Melissa Sanchez, Keith Wille, Ashley Virginia Fritz, Theresa Gelzinis, Konrad Hoetzenecker, Kavita Dave, Sandra Lindstedt, Nandor Marczin, Barbara Wilkey, Marc Schecter, James Walsh, Orla Morrissey, Caroline Landry, Siavosh Saatee, Sakhee Kotecha, Juergen Behr, Jasleen Kukreja, Göran Dellgren, Anna K. Reed, ISHLT consensus statement on the perioperative use of ECLS in lung transplantation: Part III: Postoperative considerations, The Journal of Heart and Lung Transplantation, 2025, ISSN 1053-2498, https://doi.org/10.1016/j.healun.2025.03.004.

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Document Objectives

The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no multidisciplinary consensus document has examined the perioperative considerations of how to best manage these patients. To address this challenge, this perioperative utilization of ECLS in lung transplantation consensus statement was approved for development by the International Society for Heart and Lung Transplantation Standards and Guidelines Committee. International experts across multiple disciplines, including cardiothoracic surgery, anesthesiology, critical care, pediatric pulmonology, adult pulmonology, pharmacy, psychology, physical therapy, nursing, and perfusion, were selected based on expertise and divided into subgroups examining the preoperative, intraoperative, and postoperative periods. 

Scope
Management
Diseases/Conditions (MeSH)

D016040 - Lung Transplantation

D022561 - Advanced Cardiac Life Support

D015199 - Extracorporeal Membrane Oxygenation

D008021 - Life Support Systems

D016040 - Lung Transplantation

D022561 - Advanced Cardiac Life Support

D015199 - Extracorporeal Membrane Oxygenation

D008021 - Life Support Systems

Keywords
Lung transplantation, extracorporeal circulatory life support, extracorporeal membrane oxygenation, lung transplant
Inclusion Criteria
Male, Female, Adult, Older Adult
Health Care Settings
Hospital, Operating and Recovery Room
Intended Users
Nurse, Nurse Practitioner, Physician, Physician Assistant
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