World Health Organization

This living guideline from WHO incorporates new evidence to dynamically update recommendations for clinical management and IPC for mpox infection. The GDG typically evaluates an intervention when WHO judges sufficient evidence is available to make a recommendation. While the GDG takes an individual patient perspective in making recommendations, it also considers resource implications, acceptability, feasibility, equity and human rights. Some IPC interventions are listed as good practice statements and have been formulated according to the principles outlined in the GRADE (Grading of Recommendations Assessment, Development and Evaluation) framework and further described in the Methods section of the document. This updated version of the guideline was developed according to standards and methods for trustworthy guidelines.