Document Overview

Document Title

Management of Basal Cell Carcinoma in Gorlin Syndrome

Authoring Society

Consensus and Physician Experts

Document Publication Date

Oct 24, 2025

Page Last Reviewed/Updated

May 6, 2026

Document Type

Guideline

Country of Publication

United States

Full Text Freely Available

No

Full Text Guideline

www.jaad.org/article/S0190-9622(25)03071-3/abstract

Source Citation

Brian A. Cahn, Runze Zhang, Allie M. Sidwell, Christie Mena Adam, Jessica Tiv, Rowanne Murrar, Jessica Koh, Tina Griffin, Umer Nadir, Michael D. Yi, Areeba Ahmed, Melissa Ma, Eric Koza, Misha Haq, Victoria Shi, Allen E. Bale, Jesse M. Lewin, Sean R. Christensen, Abigail Waldman, Christopher B. Harmon, Addy Alt-Holland, Lisa M. Arkin, Jamin C. Morrison, Kathleen Bogart, Michael D. Gregory, Mary E. Lohman, Anthony Rossi, Ashfaq A. Marghoob, Leonard Goldberg, S.Brian Jiang, Cerrene N. Giordano, Jennifer N. Choi, Joyce M.C. Teng, Bharat B. Mittal, Allison T. Vidimos, David J. Leffell, Yaohui Gloria Xu, Roger Haber, Paul A. Storrs, Maria Tsoukas, Faramarz H. Samie, David R. Bickers, Kishwer S. Nehal, Klara Mosterd, Elizabeth M. Billingsley, Ervin H. Epstein, Dirk Elston, Murad Alam, Taylor Hodge, Julie Breneiser, Beth A. Spiegel, Stacy Bissell, Alice George Stephenson, Nancy S. Daum, Kathlyn B. Roth, Maria Michalowski, Cindy Shelley, Paul McGoldrick, Charlotte Nadin, Meredith Weiss, Roni Rubenstein, Nour Kibbi, Brandon Worley, Anne Lynn S. Chang, Kelly L. Harms, Ross Pearlman, Jesse Hirner, Jenny Kim, Robert A. Schwartz, Rahn Kennedy Bailey, Azael Freites-Martinez, Amar Naeem Mirza, Nicholas Castner, James L. Levenson, Ramon Whitson, Nicholas Golda, Russell S. Akin, Naomi Lawrence, Addison Demer, Jeffrey F. Scott, Mara G. Beveridge, Liang Deng, Maxwell B. Sauder, Brian C. Baumann, Rene Bermudez, Jennifer G. Gill, William Clark Lambert, Armand B. Cognetta, Andrew C. Krakowski, Travis W. Blalock, Daniel I. Wasserman, Chelsea Harper, Jacqueline Dunbar-Jacob, Anisha B. Patel, Emily Y. Chu, Kavita Y. Sarin, Jean Y. Tang, Emily S. Ruiz, Keith Duffy, Bradley Merritt, Solomiya Grushchak, Ramona Behshad, William Lear, Cynthia L. Bartus, Meenal Kheterpal, Ally-Khan Somani, Joshua Eickstaedt, Jae Jung, Emily Smith, Nina Gold, Michael Walsh, Vivek Subbiah, Anthony V. Benedetto, Anna Bar, Jeremy S. Bordeaux, Conway C. Huang, Justine V. Cohen, Siegrid S. Yu, Mehran Behruj Yusuf, John Nicholas Lukens, Todd V. Cartee, Scott W. Fosko, Victor A. Neel, M.Laurin Council, Kathryn T. Shahwan, Divya Srivastava, Margo Lauterbach, James A. Solomon, Mariah R. Brown, Marta Van Beek, C.William Hanke, Patrick Lee, Ian A. Maher, Timothy S. Brown, Sailesh Konda, Nikhil I. Khushalani, Daniel B. Eisen, David R. Carr, Eli Saleeby, Mary Maloney, Marc Brown, Philip R. Cohen, Barbara A. Gilchrest, Christopher J. Miller, Thomas E. Rohrer, John A. Carucci, James Swift, Anthony E. Oro, Shahab Babakoohi, Elena B. Hawryluk, Jane M. Grant-Kels, Edward Brady Desciak, J.Thomas Landers, Clinical Practice Guidelines for the Management of Basal Cell Carcinoma in Gorlin Syndrome, Journal of the American Academy of Dermatology, 2025, ISSN 0190-9622, https://doi.org/10.1016/j.jaad.2025.10.076. (https://www.sciencedirect.com/science/article/pii/S0190962225030713)
 

Document Scope, Criteria, and Use Cases

Document Objectives

The objective of this guideline is to develop evidence-based guidelines for managing BCCs in GS, addressing both clinical and psychosocial challenges. These guidelines provide a structured framework for improving BCC management in GS, thereby enhancing clinical outcomes and patient quality of life. This process serves as a model for creating patient-centered guidelines in rare conditions with limited evidence.

Scope

Assessment and Screening, Management

Diseases/Conditions (MeSH)

D002280 - Carcinoma, Basal Cell

D002280 - Carcinoma, Basal Cell

Keywords

Gorlin Syndrome, basal cell carcinoma

Inclusion Criteria

Male, Female, Adolescent, Adult, Older Adult

Health Care Settings

Ambulatory, Operating and Recovery Room, Outpatient

Intended Users

Nurse, Nurse Practitioner, Physician, Physician Assistant