ISRS Stereotactic Body Radiation therapy for Liver Metastases Guideline Summary

Design and created by Guideline Central in participation with the International Stereotactic Radiosurgery Society.

Document Overview

Full Text Guideline: www.practicalradonc.org/article/S1879-8500(24)00272-8/abstract

Source Citation: Franzese C, Louie AV, Kotecha R, Zhang Z, Guckenberger M, Kim MS, Tree AC, Slotman BJ, Sahgal A, Scorsetti M. Stereotactic Body Radiation therapy for Liver Metastases: Systematic Review and Meta-Analysis With International Stereotactic Radiosurgery Society (ISRS) Practice Guidelines. Pract Radiat Oncol. 2025 Mar-Apr;15(2):e172-e188. doi: 10.1016/j.prro.2024.09.011. Epub 2024 Oct 16. PMID: 39419281.

Document Objectives: Liver metastases are a significant clinical challenge in cancer management, often representing a stage of disease in which curative treatment is still possible. Stereotactic body radiation therapy (SBRT) has emerged as a promising modality for treating these metastases, offering a noninvasive approach with potential for high efficacy. This systematic review and meta-analysis provides a comprehensive analysis of the efficacy and safety of SBRT in treating liver metastases, and practice recommendations are provided. This review supports the growing body of evidence that SBRT is an efficacious and safe treatment option for liver metastases. It underscores the need for careful patient selection and personalized treatment planning to optimize outcomes.

Diseases/Conditions (MeSH)

D016634 - Radiosurgery

D008113 - Liver Neoplasms

D016634 - Radiosurgery

D008113 - Liver Neoplasms

Health Care Settings: Operating and Recovery Room, Outpatient, Radiology Services