Document Overview

Document Title

Transanal Total Mesorectal Excision (taTME) for Rectal Cancer

Authoring Society

European Association of Endoscopic Surgery

Document Publication Date

Dec 18, 2025

Page Last Reviewed/Updated

May 5, 2026

Document Type

Guideline

Country of Publication

European

Full Text Freely Available

No

Full Text Guideline

link.springer.com/article/10.1007/s00464-025-12427-4

Source Citation

Huo, Bright et al. “EAES, ESCP, and ESGAR clinical practice guideline update on taTME for rectal cancer.” Surgical endoscopy, 10.1007/s00464-025-12427-4. 18 Dec. 2025, doi:10.1007/s00464-025-12427-4

Document Scope, Criteria, and Use Cases

Document Objectives

To develop updated, evidence-informed recommendations to support clinicians involved in the management of taTME; to provide guidance for hospital managers, policymakers, and patients with low- and mid-rectal cancers. We provide evidence-informed guidance on the role of taTME in the surgical management of patients with low- and mid-rectal cancers. Patients and surgeons should exercise shared-decision making to apply patient-tailored decisions when considering treatment options.

Scope

Management, Treatment

Diseases/Conditions (MeSH)

D012004 - Rectal Neoplasms

D012004 - Rectal Neoplasms

Keywords

Transanal Total Mesorectal Excision, colorectal cancer, rectal cancer

Target Patient Population

Adults with low-to mid-rectal cancers

Target Provider Population

Gastrointestinal, endoscopic, and general surgeons, any other healthcare professionals involved in the treatment of low- and mid-rectal cancers

Inclusion Criteria

Male, Female, Adult, Older Adult

Health Care Settings

Hospital, Operating and Recovery Room, Outpatient

Intended Users

Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

PICO Questions

1. Should patients receive TaTME or laparoscopic TME (laTME) for the surgical treatment of patients with low- or mid-rectal cancers?
2. Should patients receive TaTME or robotic TME (roTME) for the surgical treatment of patients with low- or mid-rectal cancers?

Supplemental Methodology Resource

Data Supplement