ESMO Metastatic Colorectal Cancer Guideline Summary - Guideline Central

Document Overview

Document Title
Metastatic Colorectal Cancer
Authoring Society

European Society for Medical Oncology

Document Publication Date
Apr 14, 2026
Page Last Reviewed/Updated
Jun 30, 2026
Document Type
Guideline
Country of Publication
European
Full Text Freely Available
Yes
Full Text Guideline
www.annalsofoncology.org/article/S0923-7534(26)00108-0/fulltext

Document Scope, Criteria, and Use Cases

Document Objectives
  • This ESMO Clinical Practice Guideline provides recommendations and algorithms for managing metastatic colorectal cancer.
  • It covers diagnosis, molecular characterisation, staging, local and systemic treatment and follow up.
  • All recommendations were formulated by a multidisciplinary group of experts from different institutions in Europe and Asia.    
  • The most recent news from clinical trials and translational research were incorporated into updated algorithms.
  • Recommendations are based on available scientific data and the authors’ collective expert opinion.
Scope
Assessment and Screening, Diagnosis, Management, Treatment
Diseases/Conditions (MeSH)

D015179 - Colorectal Neoplasms

Keywords
colorectal cancer, metastatic colorectal cancer
Inclusion Criteria
Male, Female, Adult, Older Adult
Health Care Settings
Ambulatory, Operating and Recovery Room, Outpatient, Radiology Services
Intended Users
Nurse, Nurse Practitioner, Physician, Physician Assistant
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