Document Overview

Document Title

Diagnosis, Treatment and Follow-Up of Metastatic Breast Cancer

Authoring Society

European Society for Medical Oncology

Document Publication Date

May 29, 2026

Page Last Reviewed/Updated

Jun 1, 2026

Document Type

Guideline

Country of Publication

European

Full Text Freely Available

Yes

Full Text Guideline

www.annalsofoncology.org/article/S0923-7534(26)00902-6/fulltext

Source Citation

de Azambuja, E et al. “Metastatic breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up†.” Annals of oncology : official journal of the European Society for Medical Oncology, S0923-7534(26)00902-6. 31 Dec. 2026, doi:10.1016/j.annonc.2026.05.707

Document Scope, Criteria, and Use Cases

Document Objectives

• This ESMO Clinical Practice Guideline provides key recommendations and algorithms for managing MBC.
• The guideline covers diagnosis, staging, risk assessment, treatment, disease monitoring and the patient perspective.
• The provided ESMO-MCBS scores, ESCAT scores and LoE/GoRs can aid with setting priorities.
• Treatment and management algorithms for advanced/metastatic and recurrent disease are provided.
• In clinical practice, all recommendations provided need to be discussed with patients in a shared decision-making approach.

Scope

Assessment and Screening, Diagnosis, Management, Treatment

Diseases/Conditions (MeSH)

D001943 - Breast Neoplasms

Keywords

Metastatic Breast Cancer, breast cancer

Inclusion Criteria

Female, Adult, Older Adult

Health Care Settings

Ambulatory, Operating and Recovery Room, Outpatient, Radiology Services

Intended Users

Nurse, Nurse Practitioner, Physician, Physician Assistant