Recommendations

Document Overview

Design and created by Guideline Central in participation with the American Academy of Pediatrics.

Management of Infantile Hemangiomas

American Academy of Pediatrics

Publication Date: Jan 1, 2019

Page Last Updated: May 6, 2026

American Academy of Pediatrics Grading System

Level	Aggregate Evidence Quality	Benefit or Harm Predominates	Benefit or Harm Balanced
A	Intervention: Well-designed and conducted trials, meta-analyses on applicable populations Diagnosis: Independent gold standard studies of applicable populations	Strong Recommendation	Weak Recommendation (based on balance of benefit and harm)
B	≥1 RCTs Systematic reviews or meta-analyses of moderate-quality RCTs	Moderate
C	Nonrandomized trials, observational or registry studies, systematic reviews or meta-analyses of moderate quality studies	Moderate
D	Observational or registry studies with limited design and execution, systematic reviews or meta-analyses of studies limited by design and execution	Weak Recommendation (based on low quality evidence)	No recommendation may be made
E	Expert opinion, case reports, reasoning from first principles	Strong or Moderate Recommendation

Document Overview

Document Title: Management of Infantile Hemangiomas

Authoring Society: American Academy of Pediatrics

Document Publication Date: Jan 1, 2019

Page Last Reviewed/Updated: May 6, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: pediatrics.aappublications.org/content/143/1/e20183475

Source Citation: Daniel P. Krowchuk, et al. Clinical Practice Guidelines for the Management of Infantile Hemangiomas. Pediatrics. 2019; 143(1): e20183475.

Document Scope, Criteria, and Use Cases

Scope: Assessment and Screening, Diagnosis, Management, Treatment

Keywords: Infantile hemangiomas (IHs), Lumbar syndrome, Organ IHS, PHACE, airway hemangioma (IHS), benign tumor pediatric, hemangioma, hepatic hemangioma (IHS), ulceration

Inclusion Criteria: Child, Infant

Health Care Settings: Ambulatory, Emergency Care, Hospital, Outpatient

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Number of Source Documents: 164

Literature Search Start Date: Monday, June 1, 2015

Literature Search End Date: Sunday, January 1, 2017

Methodologist involvement?: Yes

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: No

Includes benefits/harms analysis with recommendations?: Yes