Guideline Video

Guideline Resources

  • Adult Immunizations as Part of Cardiovascular Care
  • American College of Cardiology
  • August 5, 2026
  • Summary
  • Full-text

Video Transcription

Just published August 5th, 2026, the American College of Cardiology’s newest concise clinical guidance on Adult Immunizations as Part of Cardiovascular Care.

This guidance provides current recommendations on vaccination for patients with cardiovascular disease (CVD) along with more detailed rationale for those interested in the evidence informing these recommendations. The document is intended to support clinicians caring for patients with CVD and incorporates relevant and evidence-based recommendations from existing American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines, the American College of Physicians, and the Centers for Disease Control and Prevention (CDC).

In today’s rapid update, we’ll just be going over a summary of guideline recommendations within the guidance, so for the full concise clinical guidance, make sure to check it out on guidelinecentral.com

Let’s get started. 

Starting with the section on Influenza vaccine

The current recommendations for influenza vaccination of adults are as follows:

  • High-dose vaccine for adults aged ≥65 years. (Alternatives include recombinant or adjuvanted formulations.)
  • Standard-dose vaccine for all adults aged 18 to 64 years.

Next the section on Pneumococcal vaccine


The current recommendations for pneumococcal vaccination of adults are as follows:

  • All adults aged ≥50 years who have not previously received a PCV.
  • All adults aged 19 to 49 years with a chronic medical risk condition.

Then the section on COVID-19 vaccine

ACC/AHA guidelines stress the importance of vaccination. The 2023 AHA/ACC Chronic Coronary Disease Guideline includes a Class 1 recommendation for COVID-19 vaccination per public health guidelines. The 2022 AHA/ACC/HFSA Heart Failure Guideline includes a Class 2a recommendation for vaccination against respiratory diseases to reduce mortality.
In addition, the CDC Advisory Committee on Immunization Practices has recommended the following for COVID-19 vaccination:

Adults aged ≥18 years who are moderately or severely immunocompromised:

  • No prior vaccination: Complete the initial multidose series, followed by 1 additional dose 6 months after completion of the series.
  • Previously completed an initial series: Receive 2 doses, administered 6 months apart.

On to the section on RSV vaccine

The current national recommendations for RSV vaccination in adults are as follows:

  • All adults aged ≥50 years with CVD who have not previously received the RSV vaccine. The Infectious Diseases Society of America has published recommendations for those with solid organ transplants

And last the section on Zoster (Shingles) vaccine

The current national recommendations for zoster (shingles) vaccination in adults are as follows:

  • All adults aged ≥50 years should receive 2 doses of the zoster (shingles) vaccine separated by 2 to 6 months.

And there you have it. Make sure to check out the full concise clinical guidance from the American College of Cardiology and other related clinical decision support tools at guidelinecentral.com.

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