Hemorrhoids are normal vascular and connective-tissue cushions of the anal canal that become symptomatic when engorged, prolapsed, or thrombosed. Clinically, the term refers to this symptomatic state rather than to the tissue itself. Symptoms may include painless, bright red bleeding with defecation (most common), mucus discharge and soiling, pruritus ani, sensation of incomplete evacuation, dull aching or discomfort, and in some instances anemia, although this is rare. Severe pain can occur with incarceration, strangulation, or thrombosis.

Most symptomatic hemorrhoids resolve with conservative management — high-fiber diet, adequate hydration, and sitz baths. For those that fail conservative treatment, office-based procedures or surgery may be beneficial.

In this Guidelines Side-by-Side comparison, we look at the latest clinical practice guidelines from the American Society of Colon and Rectal Surgeons (ASCRS) and the American Gastroenterological Association (AGA) on hemorrhoids. 


Key Takeaways

Evaluation

  • History and Physical Examination: Both guidelines agree with completing a disease-specific history and physical examination on patients with suspected hemorrhoids.
  • Endoscopic Evaluation: The AGA recommends endoscopic evaluation for all new patients with suspected hemorrhoids before starting treatment to ensure accurate diagnosis, while the ASCRS recommends this evaluation just for certain patients with symptomatic hemorrhoids and rectal bleeding. 

Treatment

  • Non-Pharmacologic: Both the ASCRS and AGA recommend dietary and behavior modification as first-line therapies. The AGA makes note that while sitz bath is often recommended to improve symptoms scientific data is limited.
  • Pharmacologic: The ASCRS broadly states that medical therapy may help relieve symptoms. The AGA is more specific, saying that topical treatments including anesthetics, astringents, corticosteroids (for a maximum of 2 weeks), and vasoactives may be considered for symptomatic hemorrhoids, but there is little efficacy data to support this.
  • Office-Based Procedures: The ASCRS suggests that patients refractory to conservative treatment may be considered for office-based procedures based on hemorrhoid grade with banding being the most effective option. The AGA suggests both banding and infrared coagulation as safe and effective options for symptomatic hemorrhoids and should be used before surgical hemorrhoidectomy for grade 1 to 3 hemorrhoids. The AGA also adds a recommendation about informed consent, specifically that patients should be aware of the potential for pelvic sepsis as a complication. The ASCRS does not make a formal recommendation regarding informed consent but does note the very rare complication of perineal sepsis from hemorrhoid banding.
  • Surgical: Both guidelines make suggestions for surgery of thrombosed external hemorrhoids. The ASCRS suggests early excision while the AGA recommends incision and drainage. Both guidelines recommend offering hemorrhoidectomy to certain patients. The ASCRS recommends this for symptomatic combined internal and external grade 3 to 4 hemorrhoids. The AGA recommends this for grade 4 hemorrhoids and suggests offering surgical consultation to patients with grade 3 hemorrhoids who fail banding or have associated external hemorrhoids. Both guidelines report doppler-guided hemorrhoid artery ligation may result in less pain compared to excisional hemorrhoidectomy. Both guidelines agree that stapled hemorrhoidopexy should not be routinely recommended because of higher complication rates and risk for recurrence.
  • Special Patient Populations: The ASCRS did not address special patient populations. The AGA addressed hemorrhoid treatment for patients with Crohn’s disease or ulcerative colitis, women who are pregnant, and patients with cirrhosis.
    • Crohn’s disease or ulcerative colitis: Delay hemorrhoid treatment until complete remission is achieved;
    • Pregnant women: Treat with conservative management during pregnancy, after delivery may consider banding or infrared coagulation if symptoms persist or further pregnancies are planned; 
    • Cirrhosis: Determine if symptoms are due to hemorrhoids versus rectal varices. Hemorrhoids can be treated with banding or infrared coagulation (infrared coagulation is preferred in patients with significant coagulopathy).

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