Guideline Video

Guideline Resources

Video Transcription

Just published June 10th, 2026, the American College of Obstetricians and Gynecologists’ released their 2026 Maternal Immunization Schedule.

The schedule focuses on routinely recommended vaccines during pregnancy and recommended vaccines based on comorbidities or disease risk factors. The schedule includes vaccine recommendations for COVID-19, maternal RSV, Tdap, HVP, and more.

In today’s rapid update, we’ll just be going over a summary of the immunization schedule so for the full update, make sure to check it out on guidelinecentral.com

Let’s get started. 

Starting with Routinely Recommended Vaccines During Pregnancy

For Inactivated or Recombinant Influenza:

  • Administer at any time of the year, at any gestational age. Given during every pregnancy. Can be initiated while breastfeeding and while postpartum.

For COVID-19:

  • Administer at any time of the year, at any gestational age. Given during every pregnancy. Can be initiated while breastfeeding and while postpartum.

For Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap):

  • Administer at any time of the year, at 27–36 weeks of gestation. Given during every pregnancy. Can be initiated while breastfeeding and while postpartum.

For Maternal RSV (Abrysvo):

  • Administer seasonally in first eligible pregnancy, at 32 weeks 0 days–36 weeks 6 days of gestation; in subsequent pregnancies, repeat vaccination not indicated and infants should receive a monoclonal antibody. Given during every pregnancy.

Next, Recommended Vaccines Based on Comorbidities or Disease Risk Factors 

For Pneumococcal:

  • Given to specific groups during pregnancy. Can be initiated while breastfeeding and while postpartum.

For Meningococcal Conjugate (MenACWY or MenABCWY) and Meningococcal Serogroup B:

  • Given to specific groups during pregnancy. Can be initiated while breastfeeding and while postpartum.

For Hepatitis A:

  • Given to specific groups during pregnancy. Can be initiated while breastfeeding and while postpartum.

For Hepatitis B:

  • Given to specific groups during pregnancy. Can be initiated while breastfeeding and while postpartum.

For Human Papillomavirus (HPV): 

  • Can be initiated while breastfeeding and while postpartum.

For Measles-Mumps-Rubella (MMR): 

  • Contraindicated during pregnancy. Can be initiated while breastfeeding and while postpartum.

For Varicella: 

  • Contraindicated during pregnancy. Can be initiated while breastfeeding and while postpartum.

And there you have it. Make sure to check out the full schedule from the American College of Obstetricians and Gynecologists and other related clinical decision support tools at guidelinecentral.com. 

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