The Association for Molecular Pathology (AMP) is preparing for its annual conference, AMP 2025 Annual Meeting & Expo. Set for November 11 to November 15, in Boston, Massachusetts, the AMP 2025 Annual Meeting & Expo is the premiere meeting for molecular professionals. The annual meeting brings together education, science, and networking for five days packed with cutting edge showcases, collaborative events, and exciting networking opportunities.
For attendees interested in attending presentations focusing on molecular oncology topics, we curated a list of exciting presentations currently planned during the event. The following dates and times are accurate as of October 20, 2025. A full schedule of events is available on the AMP 2025 Annual Meeting & Expo website.
Thursday, November 13
Transforming Cancer Care with Cell-Free DNA Testing
- 10:15 AM – 11:45 AM
- Description: This session will focus on the latest advancements in cell-free DNA testing for both blood-based and non-blood-based samples, showcasing its applications in personalized medicine. Additionally, the session will examine the current applications, adoption challenges, and future directions of cell-free DNA testing, highlighting its impact on enhancing patient outcomes and facilitating more precise, targeted therapies.
Genomic Classification and Individualized Prognosis in Multiple Myeloma
- 1:15 PM – 2:15 PM
- Description: This presentation will explore the emerging genomic taxonomy of MM, with a focus on the integrative models that combine DNA- and RNA-based features to define biologically and clinically distinct subgroups. Attendees will learn how these findings inform prognosis, therapeutic response, and risk stratification, thereby laying the groundwork for future precision medicine approaches.
- 2:30 PM – 3:30 PM
- Description: This session will discuss the multidisciplinary collaborative AMP Clinical Practice Committee Working Group's upcoming guideline and the development of new and updated recommendations, reflecting current practices and technological advancements in cancer genomics.
- 2:30 PM – 3:30 PM
- Description: This session will provide updates from the AMP Clinical Practice Committee’s Working Group on molecular testing strategies for measurable residual disease (MRD) monitoring in acute myeloid leukemia (AML). During this session, project progress updates will be provided and attendees will have the opportunity to provide feedback to inform the upcoming publication.
- 2:30 PM – 2:45 PM
- Description: This abstract presentation takes place during the 2:30 PM Solid Tumor Abstracts presentation session where abstracts highlighted by the Solid Tumor Subdivision leadership can be evaluated through discussion with the authors.
Century-Scale Archival Sequencing of Colorectal Cancer Through a Shifting Disease Landscape
- 2:45 PM – 3:00PM
- Description: This abstract presentation takes place during the 2:30 PM Technical Topic Abstracts presentation session where abstracts highlighted by the Technical Topics Subdivision leadership can be evaluated through discussion with the authors.
- 3:00 PM – 3:15 PM
- Description: This abstract presentation takes place during the 2:30 PM Technical Topic Abstracts presentation session where abstracts highlighted by the Technical Topics Subdivision leadership can be evaluated through discussion with the authors.
Friday, November 14
- 10:15 AM – 11:45 AM
- Description: This session will review recently published expert consensus recommendations for clinical molecular laboratories for the detection of homologous recombination deficiency (HRD) in cancer, developed by the AMP Clinical Practice Committee’s PARP HRD Working Group.
Rapid Epigenomic Classification of Acute Leukemia
- 10:15 AM – 11:00 AM
- Description: During this session, attendees will learn how epigenomic classes in acute leukemia compare to existing pathologic and molecular categories, and how real-time leukemia classification can integrate with and expand existing diagnostic workflows.
Fluctuating DNA Methylation and Evolutionary History in Lymphoid Cancers
- 2:00 PM – 2:45 PM
- Description: Understanding how a cancer grew prior to diagnosis may offer valuable insight into its likely clinical course, hypothesizing that slow growing tumours would be relatively benign whereas young and fast growing tumours would be aggressive. This presentation will highlight a novel approach that uses natural fluctuations in DNA methylation to reconstruct the evolutionary history of lymphoid cancers.
Saturday, November 15
- 10:15 AM – 11:45 AM
- Description: The 2018 College of American Pathologists (CAP) / International Association for the Study of Lung Cancer (IASLC) / AMP Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment with Targeted Tyrosine Kinase Inhibitors guideline is currently undergoing a revision and update. The 2024 draft recommendation statements have recently completed an international open public comment period. Project progress updates will be provided in this session, along with the opportunity for an extended panel discussion with CAP/IASLC/AMP Lung Guideline Expert Panelists.
Putting Precision Medicine into Practice for Prostate Cancer: Impact of Genetic Testing
- 3:30 PM – 4:00 PM
- Description: During this presentation, attendees will learn about integrated germline and somatic testing in men with prostate cancer as well as cascade testing and screening for unaffected men with germline mutations.
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