We present two pediatric patients with severe uncontrolled asthma who underwent aerodigestive evaluation revealing eosinophilic asthma and eosinophilic esophageal inflammation. They were subsequently initiated on targeted biological therapy for eosinophilic inflammation with dupilumab resulting in clinical and histological improvement. These cases demonstrate that aerodigestive evaluation is an important clinical tool for characterizing asthma phenotypes and diagnosing comorbidities in children with SUA to optimize their treatment regimens.
Respiratory medicine case reports
Case Reports
English
40688717
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