Higher blood eosinophil counts in COPD patients are associated with a greater response to inhaled corticosteroid (ICS) treatment, with type 2 (T2) inflammation being the target for ICS in COPD. Current smokers have reduced responses to ICS treatment. We have investigated whether current smoking modulates the levels of T2 mediators in the airways, thereby influencing ICS responsiveness.
Keywords: COPD, smoking, sputum, type 2 inflammation
International journal of chronic obstructive pulmonary disease
Journal Article
English
41098317
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