This case-control study investigated the association between Body Mass Index (BMI), cardiovascular risk factors, and Meniere’s disease (MD). We enrolled 100 patients with definite MD and 100 age- and sex-matched controls. We assessed BMI categories, cardiovascular risk factors, and medication use. Hearing loss was evaluated via pure-tone audiometry. Multivariable logistic regression, adjusted for confounders, identified independent associations. BMI distribution differed significantly. Overweight was more prevalent in MD patients (73% vs. 22%), while normal weight was less common (19% vs. 72%; < 0.001). After adjustment, overweight remained independently associated with MD (aOR = 3.85, 95% CI: 1.92–7.72, < 0.001). Warfarin showed a protective association (aOR = 0.32, 95% CI: 0.11–0.94, = 0.04). Associations for diabetes and dyslipidemia lost significance after adjustment. Overweight is a strong, independent risk factor for MD. The protective association of warfarin suggests potential microvascular mechanisms, highlighting the importance of weight management in MD patients.
Keywords: Body mass index, Cardiovascular risk factors, Hearing loss, Meniere’s disease, Metabolic syndrome, Vestibular symptoms
Scientific reports
Journal Article
English
41720905
Guideline Central and select third party use “cookies” on this website to enhance the user experience.
This technology helps us gather statistical and analytical information to optimize the relevant content for you.
The user also has the option to opt-out which may have an effect on the browsing experience.