Patients with Ehlers-Danlos syndrome experience reduced effectiveness of lidocaine local anesthetic: a randomized cross-over clinical trial. Journal Abstract - Guideline Central

Patients with Ehlers-Danlos syndrome experience reduced effectiveness of lidocaine local anesthetic: a randomized cross-over clinical trial.

Published: 2026 Mar 03

Authors

, , , , , , , , , , , , ,

Abstract

The Ehlers-Danlos syndromes (EDS) are a collection of heritable connective tissue disorders. Local anesthetic resistance is commonly reported by patients with EDS, but there is little clinical evidence to support this finding. We hypothesized that patients with EDS would have increased anesthetic resistance using lidocaine compared with healthy controls.

Keywords: Analgesia, Anesthesia, Local, Pain Management

Source

Regional anesthesia and pain medicine

Publication Type

Journal Article

Language

English

PubMed ID

41775498

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