Levothyroxine for subclinical hypothyroidism in older adults: no evidence of benefit on quality of life or cardiovascular outcomes: a systematic review. Journal Abstract - Guideline Central

Levothyroxine for subclinical hypothyroidism in older adults: no evidence of benefit on quality of life or cardiovascular outcomes: a systematic review.

Published: 2026 Apr 01

Authors

, , , , ,

Abstract

Subclinical hypothyroidism (SCH) is highly prevalent in older adults, yet the efficacy of levothyroxine treatment in this population remains uncertain. This systematic review evaluated the efficacy of levothyroxine compared with placebo or no treatment on health-related quality of life (HRQoL) and major adverse cardiovascular events (MACE) in older adults with mild SCH.

Keywords: Aged, Cardiovascular diseases, Levothyroxine, Quality of life, Subclinical hypothyroidism, Systematic review

Source

BMC geriatrics

Publication Type

Journal Article

Language

English

PubMed ID

41922998

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