Elevated plasma klotho levels attenuate Alzheimer's disease pathologies and cognitive decline in APOE ε4 carriers. Journal Abstract - Guideline Central

Elevated plasma klotho levels attenuate Alzheimer's disease pathologies and cognitive decline in APOE ε4 carriers.

Published: 2026 Apr

Authors

, , , , , , , , , , , , , , , , , , , , , ,

Abstract

Klotho is a longevity-associated protein with established neuroprotective properties. However, it is unclear how plasma klotho levels relate to Alzheimer's disease (AD) pathologies and cognitive performance.

Keywords: Alzheimer's disease, apolipoprotein E ε4 carrier, cognitive decline, plasma klotho

Source

Alzheimer's & dementia : the journal of the Alzheimer's Association

Publication Type

Journal Article

Language

English

PubMed ID

41996134

MeSH terms

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