Night-to-night rapid eye movement sleep variability: A relevant marker of early amyloid-β deposition. Journal Abstract - Guideline Central

Night-to-night rapid eye movement sleep variability: A relevant marker of early amyloid-β deposition.

Published: 2026 Apr

Authors

, , , , , , , , , , , , , ,

Abstract

Sleep disturbances are prevalent in patients with Alzheimer's disease (AD) and may emerge before overt clinical symptoms. We characterized sleep alterations in cognitively unimpaired older adults with cerebral amyloid deposition, and assessed their associations with regional amyloid deposition and cognitive and psychoaffective outcomes.

Keywords: Alzheimer's disease pathology, PET, REM sleep, aging, amyloid, cognition, night‐to‐night sleep variability, psychoaffective symptoms, sleep

Source

Alzheimer's & dementia : the journal of the Alzheimer's Association

Publication Type

Journal Article

Language

English

PubMed ID

41996149

MeSH terms

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