Vitamin B6 predicts poor outcomes in geographically distinct populations with primary sclerosing cholangitis. Journal Abstract - Guideline Central

Vitamin B6 predicts poor outcomes in geographically distinct populations with primary sclerosing cholangitis.

Published: 2026 Apr 17

Authors

, , , , , , , , , , , , , , , , , ,

Abstract

Primary sclerosing cholangitis (PSC) has a variable disease course, complicating patient counseling and timing of liver transplantation. Vitamin B6 deficiency predicts reduced liver transplantation-free survival in Scandinavian PSC cohorts. Here, we aimed to validate this observation in U.S. and German PSC cohorts and expanded our analyses to include hepatic decompensation as a clinical outcome.

Keywords: PLP, PSC, biliary disease, deficiency, hepatic decompensation, inflammation, liver transplantation

Source

Journal of hepatology

Publication Type

Journal Article

Language

English

PubMed ID

42002000

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