Characterisation and non-pharmacological treatment of Complex Regional Pain Syndrome in under-18-year-olds: a scoping review. Journal Abstract - Guideline Central

Characterisation and non-pharmacological treatment of Complex Regional Pain Syndrome in under-18-year-olds: a scoping review.

Published: 2026 May 08

Authors

, , ,

Abstract

The aim of this review was to explore the published literature describing the presentation, characteristics, and non-pharmacological treatments of Complex Regional Pain Syndrome (CRPS) in under 18-year-olds. This scoping review was conducted in line with the Preferred Reporting Guidelines for Scoping Reviews (PRISMA-ScR). Five online databases (AMED, CINAHL + , EMBASE, EBSCO, and MEDLINE) were systematically searched with identified key terms for relevant records and screened against the eligibility criteria. Extracted data from the included studies informed a narrative synthesis. The PAGER framework was used to succinctly present gaps in the field and recommend future directions for research. Online searches yielded 140 articles. Following screening, 30 articles were included for review. Findings suggest primary symptoms included extreme pain, allodynia, and nail changes. The Budapest criteria, radiography, bone scans and laboratory examinations were commonly used diagnostic methods. Various non-pharmacological interventions were used, such as physiotherapy (home exercise), hydrotherapy, desensitisation, and cognitive behavioural therapy.

Keywords: CRPS, Children and young people, Clinical presentation, Complex Regional Pain Syndrome, Diagnosis, Occupational therapy, Paediatric, Paediatric chronic pain, Pediatric, Physiotherapy, Rehabilitation, Treatment

Source

European journal of pediatrics

Publication Type

Journal Article

Language

English

PubMed ID

42098338

MeSH terms

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