Prognostic nutritional index as a predictor of ursodeoxycholic acid response in primary biliary cholangitis: a retrospective study. Journal Abstract - Guideline Central

Prognostic nutritional index as a predictor of ursodeoxycholic acid response in primary biliary cholangitis: a retrospective study.

Published: 2026 Jun 24

Authors

, , , , , , , , ,

Abstract

Primary Biliary Cholangitis (PBC) is an autoimmune hepatic disorder characterized by the progressive destruction of intrahepatic bile ducts. Ursodeoxycholic acid (UDCA) remains the primary treatment modality; however, a subset of patients exhibits non-responsiveness to UDCA therapy. The objective of this study is to investigate the association between the Prognostic Nutritional Index (PNI) and UDCA treatment non-responsiveness in individuals diagnosed with PBC.

Keywords: Primary Biliary Cholangitis, Prognostic Nutritional Index, UDCA response

Source

BMC gastroenterology

Publication Type

Journal Article

Language

English

PubMed ID

42343243

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