The Role of Prophylaxis Antibiotics in the Prevention of Meningitis in Endonasal Anterior Skull Base Surgery: A Systematic Review and Meta-analysis. Journal Abstract - Guideline Central

The Role of Prophylaxis Antibiotics in the Prevention of Meningitis in Endonasal Anterior Skull Base Surgery: A Systematic Review and Meta-analysis.

Published: 2026 Jun

Authors

, , , , ,

Abstract

Anterior skull base surgery is commonly used for the surgical treatment of a variety of skull base lesions. One uncommon, but serious postoperative complication of this procedure is meningitis. Prophylactic antibiotics are widely used but with considerable variability in duration and regimes due to lack of guidelines. This systematic review was carried out to determine the benefit of prophylactic antibiotics in preventing meningitis in patients undergoing endonasal anterior skull base surgery.

Keywords: CSF leak, meningitis, prophylactic antibiotics, skull base surgery, transsphenoidal surgery

Source

Journal of neurological surgery. Part B, Skull base

Publication Type

Journal Article

Language

English

PubMed ID

42344725

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