Biologic-assisted immunotherapy for pediatric food allergy: a systematic review. Journal Abstract - Guideline Central

Biologic-assisted immunotherapy for pediatric food allergy: a systematic review.

Published: 2026

Authors

Abstract

Food allergies affect up to 8% of children and are a major cause of anaphylaxis, reduced quality of life, and healthcare use. Oral immunotherapy (OIT) can induce desensitization but is limited by adverse reactions, tolerability challenges, and variable long-term outcomes. Emerging biologic therapies- particularly omalizumab and dupilumab- may improve the safety and efficiency of desensitization when used alone or with immunotherapy.

Keywords: biologics, dupilumab, food allergy, omalizumab, oral immunotherapy, pediatric allergy

Source

Frontiers in allergy

Publication Type

Journal Article

Language

English

PubMed ID

42440561

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