Eight-year outcomes of testosterone suppression plus enzalutamide or a non-steroidal anti-androgen for metastatic, hormone-sensitive prostate cancer (ENZAMET; ANZUP 1304). Journal Abstract - Guideline Central

Eight-year outcomes of testosterone suppression plus enzalutamide or a non-steroidal anti-androgen for metastatic, hormone-sensitive prostate cancer (ENZAMET; ANZUP 1304).

Published: 2026 Aug 17

Authors

, , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Abstract

We previously reported that, at median follow-ups of 34 and 68 months, enzalutamide improved overall survival (OS) compared with a first-generation non-steroidal anti-androgen (NSAA) when added to testosterone suppression for metastatic hormone-sensitive prostate cancer (mHSPC). We now report longer-term outcomes, with a focus on adverse events and causes of death.

Keywords: Enzalutamide, androgen deprivation therapy, hormone-sensitive prostate cancer, non-steroidal anti-androgen, randomised controlled trial

Source

Annals of oncology : official journal of the European Society for Medical Oncology

Publication Type

Journal Article

Language

English

PubMed ID

42607762

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