Differentiated Thyroid Cancer in Adults Guidelines Pocket Guide - Guideline Central

Differentiated Thyroid Cancer in Adults

American Thyroid AssociationPublished: September 11, 2025

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  • Key Points
  • Diagnosis
  • Treatment
  • Tables
    • Pathologic Diagnostic Criteria of NIFTP
    • WHO Pathologic Classification of Differentiated Thyroid Carcinoma (WHO, 5 Edition)
    • Syndromes Associated With DTC
    • Extent of Initial Thyroid Surgery for DTC
    • AJCC/UICC TNM Staging: The 8th Ed. TNM
    • Major Changes in AJCC/UICC TNM 8th Edition-Differentiated Thyroid Carcinoma, Compared to the 7th edition
    • Genomic Changes and Combinations of Events Associated With DTC
    • Response Criteria After Initial Therapy Based on Type of Intervention
    • Summary of Recommendations for Initial RAI Following Thyroidectomy
    • Low-risk DTC With Excellent Response to Therapy De-escalation Recommendations
  • Figures and Algorithms
    • Overall DATA Framework for Clinical Management
    • ATA 2025 Estimated Risk of Structural Recurrence for PTC, FTC, and OTC
    • Nodal Levels With Corresponding Anatomic Landmarks
    • Major Histologic Subtypes of Differentiated Thyroid Carcinomas
    • DATA Framework for Initial Therapy
    • Dynamic Risk Stratification and DATA After Initial Therapy
    • DATA Framework for Persistent/Recurrent Disease
    • DATA Framework for Therapy of Radioactive lodine Resistant (RAIR) DTC
    • DATA Framework for Second-line Therapy of RAIR DTC


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