Drug Allergy Guidelines Pocket Guide - Guideline Central

Drug Allergy

American College of Allergy, Asthma, and Immunology, American Academy of Allergy, Asthma & ImmunologyPublished: February 16, 2023

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  • Key Points 
  • Tables 
    • List of Consensus-based Statements
    • Testing Procedures for Delayed HSRs
    • Contraindications to Drug Challenges
    • Open Drug Challenge Protocols for Immediate Reactions
    • Single-blind Placebo-controlled Challenge Protocols
    • Open Drug Challenge Protocols for Non-severe Delayed Reactions 
    • Testing Options for Delayed HSRs
    • HLA Associations With Delayed Drug HSRs
    • Drugs With No or Weak Evidence of Cross-reactivity
    • Groups of Beta-lactam Antibiotics that Share Side Chains
    • Immediate Hypersensitivity Cephalosporin Skin Testing
    • Criteria For 1- or 2-step TMP-SMX Oral Challenge and Exclusion
    • Classification of Common Aspirin/NSAID HSRs
    • COX-1 and COX-2 Inhibiting Medications
    • Clinical Characteristics Determining the Need for Challenge versus Desensitization in AERD Patients
    • Graded Aspirin Challenge Protocol for Patients With Cardiovascular Disease
    • Various Commonly Utilized Aspirin Desensitization Protocols for AERD
    • NSAID Classification Based on Chemical Structure
    • Rapid Low Dose Aspirin Graded Challenge for Cardiovascular Emergencies 
    • Incidence and Characteristics of Chemotherapeutic HSRs 
  • Figures 
    • Timeline of Drug HSRs
    • Recommended Approach to Beta-lactam Administration


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